×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
GeneticVariation
BEFREE
Squamous cell carcinomas showed frequent genomic amplifications of CCND1 and SOX2 and/or TP63, whereas ERBB2, VEGFA and GATA4 and GATA6 were more commonly amplified in adenocarcinomas.28052061 2017
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
AlteredExpression
BEFREE
Cyclin D1 was not expressed in normal bronchial epithelium but was detected in 7% of SMs, 15% of atypias; 18% of LGDs, 47% of HGDs, and 42% of SCC s.10344760 1999
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
GeneticVariation
BEFREE
Cyclin D1 genotype in areca-associated oral squamous cell carcinoma .12694349 2003
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
GeneticVariation
BEFREE
Cyclin D1 gene polymorphism as a risk factor for squamous cell carcinoma of the upper aerodigestive system in non-alcoholics.15063389 2004
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
AlteredExpression
BEFREE
Cyclin D1 expression and its possible regulation in chewing tobacco mediated oral squamous cell carcinoma progression.19679297 2009
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
AlteredExpression
BEFREE
CCND1 amplification and protein overexpression in oral squamous cell carcinoma of young patients.21254295 2011
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
Biomarker
BEFREE
Cyclin D1 amplification in tongue and cheek squamous cell carcinoma .22296356 2011
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
AlteredExpression
BEFREE
CCND1 amplification and cyclin D1 immunohistochemical expression in head and neck squamous cell carcinomas .23494454 2014
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
Biomarker
BEFREE
Cyclin D1 gene amplification in human laryngeal squamous cell carcinomas : prognostic significance and clinical implications.9816104 1996
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
GeneticVariation
BEFREE
A multivariable co-alteration analysis established 2 SCC subgroups: (i) patients in whom TP53 and cyclin pathway (CDKN2A and CCND1 ) alterations strongly correlated but in whom PIK3CA aberrations were less frequent; and (ii) patients with PIK3CA alterations in whom TP53 mutations were less frequent (all P ≤ 0 .001, multivariable analysis).
26030731 2015
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
Biomarker
BEFREE
Abrogation of the p16-retinoblastoma-cyclin D1 pathway in head and neck squamous cell carcinomas .
17549378 2007
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
GeneticVariation
BEFREE
Accordingly, we have examined, in patients with one squamous cell carcinoma (SCC) of the head and neck, associations between GSTM1, GSTT1, GSTM3, GSTP1, CYP2D6, CYP1A1, CYP2E1, and CCND1 genotypes and the outcome parameters, tumor extension, histological grade, and presence of nodes.
10498401 1999
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
Biomarker
BEFREE
Activation of STAT 5-cyclin D1 pathway in chewing tobacco mediated oral squamous cell carcinoma .
16172916 2005
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
GeneticVariation
BEFREE
Association of cyclin D1 polymorphism with increased susceptibility to oral squamous cell carcinoma .
15695117 2005
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
AlteredExpression
BEFREE
Association of CDK4 and CCND1 mRNA overexpression in laryngeal squamous cell carcinomas occurs without CDK4 amplification.
17139501 2007
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
GeneticVariation
BEFREE
Because the viral oncoproteins E6 and E7 from high-risk HPV types are known to promote genomic rearrangements, these findings suggest that amplification of the CCND1 gene in laryngeal SCC s may occur as a consequence of the genomic instability associated with HPV infection.
9829720 1998
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
GeneticVariation
BEFREE
Both SCC s with less Cyclin D1 gene copies than centromere 11 signals showed a weak protein expression.
15723720 2005
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
Biomarker
BEFREE
Coamplification of the hst and bcl-1 oncogenes in advanced squamous cell carcinomas of the head and neck.
8398339 1993
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
GeneticVariation
BEFREE
Correlation between p53 mutation and cyclin D1 amplification in had and neck squamous cell carcinoma .
9192552 1997
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
AlteredExpression
BEFREE
Correlation of cyclin D1 expression with aggressive DNA pattern in patients with tobacco-related intraoral squamous cell carcinoma .
21537090 2011
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
Biomarker
BEFREE
Cyclin D1/PRAD 1 , a cell cycle-related gene mapped to chromosome 11q13, has been found to be amplified in some breast cancers and squamous cell carcinomas of the head and neck, and esophagus.
7942638 1994
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
Biomarker
BEFREE
Deregulation of cyclin D1 is a frequent event in oral squamous cell carcinoma .
21042715 2010
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
Biomarker
BEFREE
Differential expression of key cell cycle genes (p16/cyclin D1 /pRb) in head and neck squamous carcinomas .
10092061 1999
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
PosttranslationalModification
BEFREE
Differentiation-inducing factor-1 induces cyclin D1 degradation through the phosphorylation of Thr286 in squamous cell carcinoma .
16153639 2005
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Squamous cell carcinoma
0.400
AlteredExpression
BEFREE
Expression and inactivation of glycogen synthase kinase 3 alpha/ beta and their association with the expression of cyclin D1 and p53 in oral squamous cell carcinoma progression.
25645517 2015