×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Exome sequencing identifies nonsegregating nonsense ATM and PALB2 variants in familial pancreatic cancer.
23561644 2013
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
26681312 2016
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Penetrance analysis of the PALB2 c.1592delT founder mutation.
18628482 2008
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Implementation of next-generation sequencing for molecular diagnosis of hereditary breast and ovarian cancer highlights its genetic heterogeneity.
27553368 2016
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Heterozygous mutations in the PALB2 hereditary breast cancer predisposition gene impact on the three-dimensional nuclear organization of patient-derived cell lines.
23341105 2013
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
A high frequency of PALB2 mutations in Jamaican patients with breast cancer.
28194609 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Rare germline mutations in PALB2 and breast cancer risk: a population-based study.
22241545 2012
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Novel germline PALB2 truncating mutations in African American breast cancer patients.
21932393 2012
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Frequency of pathogenic germline mutation in CHEK2, PALB2, MRE11, and RAD50 in patients at high risk for hereditary breast cancer.
27783279 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Prevalence of PALB2 mutations in the Creighton University Breast Cancer Family Registry.
25794774 2015
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Outcomes of retesting BRCA negative patients using multigene panels.
27878467 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
PALB2: a novel inactivating mutation in a Italian breast cancer family.
20852946 2010
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
A PALB2 mutation associated with high risk of breast cancer.
21182766 2010
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Germline mutations of PALB2 gene in a sequential series of Chinese patients with breast cancer.
28825143 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Inherited Mutations in Women With Ovarian Carcinoma.
26720728 2016
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Germline and somatic mutations in homologous recombination genes predict platinum response and survival in ovarian, fallopian tube, and peritoneal carcinomas.
24240112 2014
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Breast-cancer risk in families with mutations in PALB2.
25099575 2014
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Inherited mutations in cancer susceptibility genes are common among survivors of breast cancer who develop therapy-related leukemia.
26641009 2016
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Mutations predisposing to breast cancer in 12 candidate genes in breast cancer patients from Poland.
25330149 2015
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer.
27433846 2016
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
PALB2 mutations in breast cancer patients from a multi-ethnic region in northwest China.
26489409 2015
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Genetic Cancer Risk Assessment for Breast Cancer in Latin America.
28453507 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Candidate gene analysis of BRCA1/2 mutation-negative high-risk Russian breast cancer patients.
25619955 2015
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
PALB2 sequencing in Italian familial breast cancer cases reveals a high-risk mutation recurrent in the province of Bergamo.
24556926 2014
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Analysis of PALB2 in a cohort of Italian breast cancer patients: identification of a novel PALB2 truncating mutation.
25666743 2015