×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants.
22102614 2012
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
GeneticVariation
UNIPROT
Germline mutation analysis of MLH1 and MSH2 in Malaysian Lynch syndrome patients.
22371642 2012
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
GeneticVariation
UNIPROT
A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants.
22102614 2012
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
Frequency of mutations in mismatch repair genes in a population-based study of women with ovarian cancer.
23047549 2012
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
GeneticVariation
CLINVAR
Integrated analysis of unclassified variants in mismatch repair genes.
21239990 2011
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
Cancer risks associated with germline mutations in MLH1, MSH2, and MSH6 genes in Lynch syndrome.
21642682 2011
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
Integrated analysis of unclassified variants in mismatch repair genes.
21239990 2011
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
Characterization of germline mutations of MLH1 and MSH2 in unrelated south American suspected Lynch syndrome individuals.
21681552 2011
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
Verification of the three-step model in assessing the pathogenicity of mismatch repair gene variants.
21120944 2011
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
GeneticVariation
UNIPROT
Verification of the three-step model in assessing the pathogenicity of mismatch repair gene variants.
21120944 2011
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
Comparative in silico analyses and experimental validation of novel splice site and missense mutations in the genes MLH1 and MSH2.
19669161 2010
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
Risk of urothelial bladder cancer in Lynch syndrome is increased, in particular among MSH2 mutation carriers.
20591884 2010
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
Current clinical criteria for Lynch syndrome are not sensitive enough to identify MSH6 mutation carriers.
20587412 2010
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
Evaluating Lynch syndrome in very early onset colorectal cancer probands without apparent polyposis.
19731080 2010
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
Major contribution from recurrent alterations and MSH6 mutations in the Danish Lynch syndrome population.
18566915 2009
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
A study on MSH2 and MLH1 mutations in hereditary nonpolyposis colorectal cancer families from the Basque Country, describing four new germline mutations.
19760518 2009
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications.
19659756 2009
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
High frequency of exon deletions and putative founder effects in French Canadian Lynch syndrome families.
19459153 2009
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
Classifying MLH1 and MSH2 variants using bioinformatic prediction, splicing assays, segregation, and tumor characteristics.
19267393 2009
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
Mechanisms of pathogenicity in human MSH2 missense mutants.
18951462 2008
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
GeneticVariation
UNIPROT
MSH2 missense mutations and HNPCC syndrome: pathogenicity assessment in a human expression system.
18781619 2008
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
MSH2 missense mutations and HNPCC syndrome: pathogenicity assessment in a human expression system.
18781619 2008
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
GeneticVariation
CLINVAR
Accurate classification of MLH1/MSH2 missense variants with multivariate analysis of protein polymorphisms-mismatch repair (MAPP-MMR).
18383312 2008
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
GeneticVariation
UNIPROT
Functional analysis of HNPCC-related missense mutations in MSH2.
18822302 2008
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
GeneticVariation
UNIPROT
Mechanisms of pathogenicity in human MSH2 missense mutants.
18951462 2008