×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
CausalMutation
CLINVAR
Frameshift Mutations (Deletion at Codon 1309 and Codon 849) in the APC Gene in Iranian FAP Patients: a Case Series and Review of the Literature.
25317407 2014
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
GeneticVariation
CLINVAR
ACMG technical standards and guidelines for genetic testing for inherited colorectal cancer (Lynch syndrome, familial adenomatous polyposis, and MYH-associated polyposis).
24310308 2014
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
CausalMutation
CLINVAR
Two Chinese pedigrees for adenomatous polyposis coli: new mutations at codon 1309 and predisposition to phenotypic variations.
24664542 2014
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
CausalMutation
CLINVAR
A de novo germline mutation of APC for inheritable colon cancer in a Chinese family using multigene next generation sequencing.
24735542 2014
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
GeneticVariation
CLINVAR
Colorectal tumors from APC*I1307K carriers principally harbor somatic APC mutations outside the A8 tract.
24416237 2014
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
CausalMutation
CLINVAR
Fatal extraintestinal adrenal malignancy in a 12-year-old girl with familial adenomatous polyposis.
23575299 2014
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
GeneticVariation
CLINVAR
A unique profile of adenomatous polyposis coli gene mutations in Iranian patients suffering sporadic colorectal cancer.
24518971 2014
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
GeneticVariation
CLINVAR
Germline variation in cancer-susceptibility genes in a healthy, ancestrally diverse cohort: implications for individual genome sequencing.
24728327 2014
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
CausalMutation
CLINVAR
The UMD-APC database, a model of nation-wide knowledge base: update with data from 3,581 variations.
24599579 2014
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
Biomarker
CTD_human
Resveratrol prevents tumorigenesis in mouse model of Kras activated sporadic colorectal cancer by suppressing oncogenic Kras expression.
25280562 2014
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
Biomarker
CTD_human
The concentrations of EGFR, LRG1, ITIH4, and F5 in serum correlate with the number of colonic adenomas in ApcPirc/+ rats.
25200834 2014
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
GeneticVariation
CLINVAR
APC germline mutations in individuals being evaluated for familial adenomatous polyposis: a review of the Mayo Clinic experience with 1591 consecutive tests.
23159591 2013
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
CausalMutation
CLINVAR
Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis.
23085758 2013
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
SusceptibilityMutation
CLINVAR
The APC p.I1307K polymorphism is a significant risk factor for CRC in average risk Ashkenazi Jews.
23896379 2013
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
GeneticVariation
CLINVAR
The APC p.I1307K polymorphism is a significant risk factor for CRC in average risk Ashkenazi Jews.
23896379 2013
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
CausalMutation
CLINVAR
Multifocal hepatic neoplasia in 3 children with APC gene mutation.
23715166 2013
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
CausalMutation
CLINVAR
Mutational spectrum of the APC and MUTYH genes and genotype-phenotype correlations in Brazilian FAP, AFAP, and MAP patients.
23561487 2013
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
GeneticVariation
CLINVAR
Novel mutations of the APC gene and genetic consequences of splicing mutations in the Czech FAP families.
22987206 2013
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
GeneticVariation
CLINVAR
APC polymorphisms and the risk of colorectal neoplasia: a HuGE review and meta-analysis.
23576677 2013
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
CausalMutation
CLINVAR
APC germline mutations in individuals being evaluated for familial adenomatous polyposis: a review of the Mayo Clinic experience with 1591 consecutive tests.
23159591 2013
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
CausalMutation
CLINVAR
Novel mutations of the APC gene and genetic consequences of splicing mutations in the Czech FAP families.
22987206 2013
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
CausalMutation
CLINVAR
Clinical characterization and mutation spectrum in Hispanic families with adenomatous polyposis syndromes.
23460355 2013
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
SusceptibilityMutation
CLINVAR
APC polymorphisms and the risk of colorectal neoplasia: a HuGE review and meta-analysis.
23576677 2013
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
GeneticVariation
CLINVAR
Deep intronic APC mutations explain a substantial proportion of patients with familial or early-onset adenomatous polyposis.
22431159 2012
×
Entrez Id: 324
Gene Symbol: APC
APC
Polyposis, Adenomatous Intestinal
0.400
CausalMutation
CLINVAR
Colon cancer prevention by detection of APC gene mutation in a family with attenuated familial adenomatous polyposis.
23244118 2012