Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 25824
Gene Symbol: PRDX5
PRDX5
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 AlteredExpression BEFREE An upregulated expression of Prdx3 and Prdx5 has been reported in different cancer types, such as breast, ovarian, endometrial, and lung cancers, as well as in Hodgkin's lymphoma and hepatocellular carcinoma. 31500275

2019

Entrez Id: 7001
Gene Symbol: PRDX2
PRDX2
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 AlteredExpression BEFREE Validation of proteins implicated in sperm fertility potential by Western Blot demonstrated that peroxiredoxin 2 (PRDX 2) was underexpressed (p=0.015), and transferrin (p=0.045) and SERPIN A5 (p=0.010) protein levels were overexpressed in spermatozoa of men with HD. 31385466

2019

Entrez Id: 57591
Gene Symbol: MRTFA
MRTFA
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 AlteredExpression BEFREE While cells from the Hodgkin lymphoma treated patients had a phenotype close to healthy controls, cells from the undiagnosed triplet had increased MKL1 mRNA, increased MKL1 protein, and elevated expression of MKL1-dependent genes. 31582539

2019

Entrez Id: 55783
Gene Symbol: CMTR2
CMTR2
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 Biomarker BEFREE Considering Cox and three parametric event-time models, the parametric AFT log-normal had the best efficiency in determining factors influencing HD patients survival. 31185926

2019

Entrez Id: 407
Gene Symbol: ARR3
ARR3
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 Biomarker BEFREE This review focuses on application of CAR-T cells in hematologic malignancies beyond targeting CD19, with specific attention to Hodgkin's lymphoma and acute myeloid leukemia. 30632631

2019

Entrez Id: 7218
Gene Symbol: TRP-AGG2-6
TRP-AGG2-6
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 Biomarker BEFREE In accordance, cortisol level tended to be higher in fish fed both supplemented diets at LD compared to fish fed CTRL, but was lower in fish fed TRP4 than in those fed TRP2 under HD condition. 31118899

2019

Entrez Id: 846
Gene Symbol: CASR
CASR
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 Biomarker BEFREE This review focuses on application of CAR-T cells in hematologic malignancies beyond targeting CD19, with specific attention to Hodgkin's lymphoma and acute myeloid leukemia. 30632631

2019

Entrez Id: 151176
Gene Symbol: ERFE
ERFE
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 Biomarker BEFREE Serum ERFE is associated with mortality and CV events in CKD and in HD patients, and treatment by ESA amplifies the risk for this combined end-point in HD patients. 30995819

2019

Entrez Id: 5903
Gene Symbol: RANBP2
RANBP2
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 Biomarker BEFREE In accordance, cortisol level tended to be higher in fish fed both supplemented diets at LD compared to fish fed CTRL, but was lower in fish fed TRP4 than in those fed TRP2 under HD condition. 31118899

2019

Entrez Id: 5309
Gene Symbol: PITX3
PITX3
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 Biomarker BEFREE PTX-3 increased only in HD patients and was highest at M0, and it then gradually decreased. 30952879

2019

Entrez Id: 693122
Gene Symbol: MIR421
MIR421
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 AlteredExpression BEFREE In this study, we investigated the correlation between serum levels of miR-421 and ACE2 transcripts in circulating leukocytes of healthy individuals (NP), CKD (3-5) and haemodialysis (HD) patients. 30326474

2019

Entrez Id: 10999
Gene Symbol: SLC27A4
SLC27A4
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 GeneticVariation BEFREE Prognostic Utility of the IPS 3 Score for Predicting Outcomes in Advanced Hodgkin Lymphoma. 30579722

2019

Entrez Id: 6696
Gene Symbol: SPP1
SPP1
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 AlteredExpression BEFREE Serum osteopontin level is associated with heart valve calcification in HD patients, but there was no relationship found with FGF-23. 30369401

2019

Entrez Id: 5091
Gene Symbol: PC
PC
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 Biomarker BEFREE Our results suggest that PC and PS deficiencies may be related to survival in HD patients. 31138132

2019

Entrez Id: 2671
Gene Symbol: GFER
GFER
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 Biomarker BEFREE We generated phenotype-disease bipartite graphs for HPO-Orphanet, EMR, and enriched knowledge base HPO-Orphanet + and conducted a case study on Hodgkin lymphoma to compare performance on differential diagnosis among these three graphs. 30764825

2019

Entrez Id: 3111
Gene Symbol: HLA-DOA
HLA-DOA
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 AlteredExpression BEFREE Of note, brentuximab vedotin is an antibody-drug conjugate that targets CD30, another lymphocyte antigen expressed on the cell surface of both Hodgkin lymphoma (a variant of B-cell lymphoma) and some T-cell lymphomas. 31580408

2019

Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 GeneticVariation BEFREE A total thyroidectomy with bilateral lymph node dissection was performed and the microscopic examination revealed a 2-cm PTC with BRAF mutation and HL (mixed cellularity) in the bilateral lymph nodes. 30653166

2019

Entrez Id: 3683
Gene Symbol: ITGAL
ITGAL
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 AlteredExpression BEFREE Interestingly, cells from the triplet treated for Hodgkin lymphoma in 1985 contained two subpopulations: one with high expression of CD11a that behaved like control cells and the other with low expression of CD11a that formed large tumors in vivo similar to cells from the undiagnosed triplet. 31582539

2019

Entrez Id: 6687
Gene Symbol: SPG7
SPG7
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 Biomarker BEFREE This review focuses on application of CAR-T cells in hematologic malignancies beyond targeting CD19, with specific attention to Hodgkin's lymphoma and acute myeloid leukemia. 30632631

2019

Entrez Id: 653108
Gene Symbol: CXADRP1
CXADRP1
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 Biomarker BEFREE This review focuses on application of CAR-T cells in hematologic malignancies beyond targeting CD19, with specific attention to Hodgkin's lymphoma and acute myeloid leukemia. 30632631

2019

Entrez Id: 5971
Gene Symbol: RELB
RELB
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 Biomarker BEFREE BCL2 was exclusively controlled by Rel-B in HL. 30941572

2019

Entrez Id: 51477
Gene Symbol: ISYNA1
ISYNA1
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 GeneticVariation BEFREE Prognostic Utility of the IPS 3 Score for Predicting Outcomes in Advanced Hodgkin Lymphoma. 30579722

2019

Entrez Id: 3929
Gene Symbol: LBP
LBP
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 AlteredExpression BEFREE Our aim is to investigate the relationship between circulating levels of LBP, and various metabolic and inflammatory markers in HD patients. 30219816

2019

Entrez Id: 9970
Gene Symbol: NR1I3
NR1I3
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 Biomarker BEFREE This review focuses on application of CAR-T cells in hematologic malignancies beyond targeting CD19, with specific attention to Hodgkin's lymphoma and acute myeloid leukemia. 30632631

2019

Entrez Id: 192142
Gene Symbol: RLS1
RLS1
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.010 Biomarker BEFREE Restless legs syndrome/Willis-Ekbom disease (RLS/WED) is a common sensorimotory disorder affecting almost 30% of hemodialysis (HD) patients. 28682991

2018