Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 56994
Gene Symbol: CHPT1
CHPT1
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.100 Biomarker BEFREE These data demonstrate that the protection from apoptosis induced in response to CPT-11 treatment is effectively inhibited by the transient inhibition of NF-kappaB in a variety of human colon cancer cell lines and in a tumor xenograft model, resulting in a significantly enhanced tumoricidal response to CPT-11 via increased induction of apoptosis. 10811101

2000

Entrez Id: 56994
Gene Symbol: CHPT1
CHPT1
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.100 GeneticVariation BEFREE Determination of the presence of a K-ras mutation may predict survival in patients with progressive colon cancer after treatment with 5-fluorouracil who receive CPT-11. 9345343

1997