Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0025500
Disease: Mesothelioma
Mesothelioma 		0.300 AlteredExpression BEFREE Coordinate expression of the WT1 protein and its putative transcriptional target genes was determined by correlating WT1 immunostaining with epidermal growth factor receptor (EGF-R) and insulin-like growth factor 1 receptor (IGF-1R) expression on MM and NNM; no significant correlation was found, irrespective of p53 expression status. 9072005

1997
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0025500
Disease: Mesothelioma
Mesothelioma 		0.300 AlteredExpression BEFREE We postulated that high levels of MDM2 might alter p53 and retinoblastoma tumour-suppressor function in mesothelioma. 8932331

1996
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0025500
Disease: Mesothelioma
Mesothelioma 		0.300 GeneticVariation BEFREE Seven lung carcinomas and 5 malignant mesotheliomas were analyzed for p53 mutations; only 1 (in a lung adenocarcinoma) was detected. 7591226

1995
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0025500
Disease: Mesothelioma
Mesothelioma 		0.300 Biomarker BEFREE We conclude that there is immunoreactivity for p53 protein in some mesotheliomas. p53 protein immunoreactivity could be used to discriminate between neoplastic and reactive mesothelium. 1484318

1992
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0025500
Disease: Mesothelioma
Mesothelioma 		0.300 Biomarker BEFREE These data suggest that neither p53 alteration nor K-ras activation constitutes a critical step in the development of human mesothelioma. 1568228

1992
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0025500
Disease: Mesothelioma
Mesothelioma 		0.300 Biomarker BEFREE We have examined four mesothelioma cell lines for genetic abnormalities in p53. 1913660

1991