Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.400 GeneticVariation BEFREE Functional -1562 C-to-T polymorphism in matrix metalloproteinase-9 (MMP-9) promoter is associated with the risk for oral squamous cell carcinoma in younger male areca users. 17617834

2007

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.400 AlteredExpression LHGDN Thus, the NF-kappaB role has been proved in the regulation of MMP-9 transcription in SCC. 17922642

2007

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.400 GeneticVariation LHGDN Functional -1562 C-to-T polymorphism in matrix metalloproteinase-9 (MMP-9) promoter is associated with the risk for oral squamous cell carcinoma in younger male areca users. 17617834

2007

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.400 Biomarker LHGDN Correlation of expression of Ki-67, EGFR, c-erbB-2, MMP-9, p53, bcl-2, CD34 and cell cycle analysis with survival in head and neck squamous cell cancer. 17310847

2006

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.400 Biomarker LHGDN These results indicate that MMP3, MMP9, and TGFbeta1 are important for the modulation, composition, and maintenance of the ECM in oral SCC. 15033492

2004

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.400 AlteredExpression BEFREE All EBER-positive SCCs were infected with EBV type A. LMP1 expression was detected in 36 of 59 (61%) patients with latent EBV infection and MMP9 in 41 of these 59 (69%). 15229899

2004

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.400 AlteredExpression BEFREE Integrin alphavbeta6 is induced in SCC and appears to be involved in up-regulation of MMP-9 expression by oral keratinocytes and promotion of their migration. 14694517

2004

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.400 Biomarker LHGDN Expression of c-erbB receptors, MMPs and VEGF in squamous cell carcinoma of the head and neck. 15254682

2004

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.400 AlteredExpression LHGDN Circulating 92-kilodalton matrix metalloproteinase (MMP-9) activity is enhanced in the euglobulin plasma fraction of head and neck squamous cell carcinoma. 11920505

2002

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.400 AlteredExpression LHGDN This study was designed to investigate the expression of MMP-2, MMP-9 and TIMP-1, TIMP-2 in human squamous cell carcinomas of uterine cervix, and the association with invasion and metastasis of human squamous cell carcinoma of uterine cervix. 12479097

2002

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.400 AlteredExpression LHGDN Overexpression of MMP-2 and MMP-9 in squamous cell carcinomas of immunosuppressed patients. 12029498

2002

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.400 AlteredExpression BEFREE To determine how JNK1 activity regulated MMP-9 expression in human squamous cell carcinoma lines, we overexpressed this kinase in SCC25 cells. 11326313

2001