Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 CausalMutation CGI

Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 Biomarker CTD_human

Entrez Id: 843
Gene Symbol: CASP10
CASP10
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 CausalMutation CGI

Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.580 Biomarker CTD_human Antitumor action of the MET tyrosine kinase inhibitor crizotinib (PF-02341066) in gastric cancer positive for MET amplification. 22729845

2012

Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.580 Biomarker CTD_human MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib. 22042947

2011

Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.580 GenomicAlterations CGI

Entrez Id: 472
Gene Symbol: ATM
ATM
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.520 Biomarker CTD_human Loss-of-function variants in ATM confer risk of gastric cancer. 26098866

2015

Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.520 Biomarker CTD_human Upregulation of heme oxygenase-1 and p21 confers resistance to apoptosis in human gastric cancer cells. 14647439

2004

Entrez Id: 472
Gene Symbol: ATM
ATM
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.520 GenomicAlterations CGI

Entrez Id: 472
Gene Symbol: ATM
ATM
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.520 CausalMutation CGI

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.500 Biomarker CTD_human Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. 24816253

2014

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.500 Biomarker CTD_human Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. 22484628

2012

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.460 Biomarker CTD_human Point mutations of K-ras and H-ras genes in forestomach neoplasms from control B6C3F1 mice and following exposure to 1,3-butadiene, isoprene or chloroprene for up to 2-years. 11397402

2001

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.460 Biomarker CTD_human DNA adduct measurements, cell proliferation and tumor mutation induction in relation to tumor formation in B6C3F1 mice fed coal tar or benzo[a]pyrene. 10874023

2000

Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.450 Biomarker CTD_human Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray. 16367923

2006

Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.420 CausalMutation CGI

Entrez Id: 10395
Gene Symbol: DLC1
DLC1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.410 Therapeutic CTD_human Genomic alterations in BCL2L1 and DLC1 contribute to drug sensitivity in gastric cancer. 26401016

2015

Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.410 CausalMutation CGI

Entrez Id: 8314
Gene Symbol: BAP1
BAP1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker CTD_human Germline BAP1 Mutational Landscape of Asbestos-Exposed Malignant Mesothelioma Patients with Family History of Cancer. 26719535

2016

Entrez Id: 8314
Gene Symbol: BAP1
BAP1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker CTD_human Inference on germline BAP1 mutations and asbestos exposure from the analysis of familial and sporadic mesothelioma in a high-risk area. 25231345

2015

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker CTD_human Expression of AFP and STAT3 is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in AFP-producing gastric cancer cells. 23382965

2013

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker CTD_human A genetic variant in 3'-untranslated region of cyclooxygenases-2 gene is associated with risk of gastric cancer in a Chinese population. 22385256

2012

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker CTD_human Capsaicin consumption, Helicobacter pylori CagA status and IL1B-31C>T genotypes: a host and environment interaction in gastric cancer. 22414649

2012

Entrez Id: 1019
Gene Symbol: CDK4
CDK4
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker CTD_human Cyclin D1/cdk4, estrogen receptors α and β, in N-methyl-N'-nitro-N-nitrosoguanidine-induced rat gastric carcinogenesis: immunohistochemical study. 21628965

2011

Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker CTD_human DNA repair gene and MTHFR gene polymorphisms as prognostic markers in locally advanced adenocarcinoma of the esophagus or stomach treated with cisplatin and 5-fluorouracil-based neoadjuvant chemotherapy. 21347786

2011