Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE Clinical characteristics of TIMP2, MMP2, and MMP9 gene polymorphisms in colorectal cancer. 21261731

2011

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE MMP-2 geno-phenotype is prognostic for colorectal cancer survival, whereas MMP-9 is not. 18506186

2008

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE MMP-9-hemopexin domain hampers adhesion and migration of colorectal cancer cells. 17332939

2007

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Mean TGFbeta1, MMP-9, and Ki-67 LI in CC were significantly higher (p < 0.01, 0.01, and 0.01, respectively) than in HGD polyps. 17394006

2007

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE In addition, the MMP-9 279R allele may lead to a younger age of onset of colorectal cancer. 17729419

2007

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Tumor epithelial cell matrix metalloproteinase 9 is a target for antimetastatic therapy in colorectal cancer. 16551873

2006

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE A prospective study to assess the value of MMP-9 in improving the appropriateness of urgent referrals for colorectal cancer. 17059590

2006

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Furthermore, involvement of MMP-2 and MMP-9 in experimental models of colorectal cancer is reviewed. 15588763

2004

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Here we examined the expression of RECK and one of its targets, MMP-9, in colorectal cancer tissue. 15328199

2004

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Our study investigates the distribution of MMP-2 and MMP-9 in colorectal cancer, the correlation with plasma levels, changes following surgical resection and whether plasma levels reflect clinical staging and disease course. 14520690

2003

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE To evaluate the expression of TIMP-1, TIMP-2, MMP-2, and MMP-9 in human colorectal cancer, surgical specimens of primary colorectal cancer (66 cases) and liver metastases (10 cases) were examined by Northern and dot-blot hybridization. 8895669

1996

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression BEFREE Prediction of colorectal cancer relapse and survival via tissue RNA levels of matrix metalloproteinase-9. 8955659

1996

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression BEFREE Our data demonstrate a distinct pattern of MMP-9 and TIMP-1 mRNA expression in colorectal cancer and liver metastases suggesting distinct cellular origins as well as separate patterns of regulation. 7669564

1995