DisGeNET - a database of gene-disease associations

Source: GWASDB

Disease: Serum LDL cholesterol measurement ×

The Variant filter does not apply in GDA tabs

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	3949
Gene Symbol:	LDLR

LDLR

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study.

23100282

2013

Entrez Id:	285489
Gene Symbol:	DOK7

DOK7

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013

Entrez Id:	10452
Gene Symbol:	TOMM40

TOMM40

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study.

23100282

2013

Entrez Id:	55219
Gene Symbol:	MACO1

MACO1

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013

Entrez Id:	29881
Gene Symbol:	NPC1L1

NPC1L1

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013

Entrez Id:	8897
Gene Symbol:	MTMR3

MTMR3

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013

Entrez Id:	54957
Gene Symbol:	TXNL4B

TXNL4B

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013

Entrez Id:	3949
Gene Symbol:	LDLR

LDLR

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013

Entrez Id:	6311
Gene Symbol:	ATXN2

ATXN2

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Large-scale association analysis identifies new risk loci for coronary artery disease.

23202125

2013

Entrez Id:	10019
Gene Symbol:	SH2B3

SH2B3

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Large-scale association analysis identifies new risk loci for coronary artery disease.

23202125

2013

Entrez Id:	6580
Gene Symbol:	SLC22A1

SLC22A1

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013

Entrez Id:	64241
Gene Symbol:	ABCG8

ABCG8

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013

Entrez Id:	3122
Gene Symbol:	HLA-DRA

HLA-DRA

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013

Entrez Id:	85440
Gene Symbol:	DOCK7

DOCK7

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013

Entrez Id:	348
Gene Symbol:	APOE

APOE

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study.

23100282

2013

Entrez Id:	54577
Gene Symbol:	UGT1A7

UGT1A7

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013

Entrez Id:	3156
Gene Symbol:	HMGCR

HMGCR

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013

Entrez Id:	64241
Gene Symbol:	ABCG8

ABCG8

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study.

23100282

2013

Entrez Id:	54576
Gene Symbol:	UGT1A8

UGT1A8

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013

Entrez Id:	57678
Gene Symbol:	GPAM

GPAM

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013

Entrez Id:	7150
Gene Symbol:	TOP1

TOP1

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013

Entrez Id:	54575
Gene Symbol:	UGT1A10

UGT1A10

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013

Entrez Id:	2444
Gene Symbol:	FRK

FRK

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013

Entrez Id:	6597
Gene Symbol:	SMARCA4

SMARCA4

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Large-scale association analysis identifies new risk loci for coronary artery disease.

23202125

2013

Entrez Id:	675
Gene Symbol:	BRCA2

BRCA2

CUI:	C0428474
Disease:	Serum LDL cholesterol measurement

Serum LDL cholesterol measurement

0.100

GeneticVariation

GWASDB

Discovery and refinement of loci associated with lipid levels.

24097068

2013