×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
[Gene (SCN5A) mutation analysis of a Chinese family with Brugada syndrome].
18341814
2007
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
A novel SCN5A mutation, F1344S, identified in a patient with Brugada syndrome and fever-induced ventricular fibrillation.
16616735
2006
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
[Novel SCN5A gene mutations associated with Brugada syndrome: V95I, A1649V and delF1617].
17081365
2006
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Compound heterozygous mutations P336L and I1660V in the human cardiac sodium channel associated with the Brugada syndrome.
17075016
2006
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
High risk for bradyarrhythmic complications in patients with Brugada syndrome caused by SCN5A gene mutations.
16325048
2005
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Novel Brugada syndrome-causing mutation in ion-conducting pore of cardiac Na+ channel does not affect ion selectivity properties.
16266370
2005
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Double SCN5A mutation underlying asymptomatic Brugada syndrome.
15851320
2005
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Genetic analysis of the cardiac sodium channel gene SCN5A in Koreans with Brugada syndrome.
15338453
2004
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
A trafficking defective, Brugada syndrome-causing SCN5A mutation rescued by drugs.
15023552
2004
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Nav1.5 E1053K mutation causing Brugada syndrome blocks binding to ankyrin-G and expression of Nav1.5 on the surface of cardiomyocytes.
15579534
2004
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Genetic and biophysical basis of sudden unexplained nocturnal death syndrome (SUNDS), a disease allelic to Brugada syndrome.
11823453
2002
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Genotype-phenotype relationship in Brugada syndrome: electrocardiographic features differentiate SCN5A-related patients from non-SCN5A-related patients.
12106943
2002
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Novel mutations in domain I of SCN5A cause Brugada syndrome.
12051963
2002
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Natural history of Brugada syndrome: insights for risk stratification and management.
11901046
2002
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Novel SCN5A mutation leading either to isolated cardiac conduction defect or Brugada syndrome in a large French family.
11748104
2001
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Inherited Brugada and long QT-3 syndrome mutations of a single residue of the cardiac sodium channel confer distinct channel and clinical phenotypes.
11410597
2001
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Cardiac Na(+) channel dysfunction in Brugada syndrome is aggravated by beta(1)-subunit.
10618304
2000
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Ionic mechanisms responsible for the electrocardiographic phenotype of the Brugada syndrome are temperature dependent.
10532948
1999
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Human SCN5A gene mutations alter cardiac sodium channel kinetics and are associated with the Brugada syndrome.
10690282
1999
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Brugada Syndrome 1
0.910
GeneticVariation
UNIPROT
Genetic basis and molecular mechanism for idiopathic ventricular fibrillation.
9521325
1998
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Hereditary bundle branch system defect
0.980
GeneticVariation
UNIPROT
MOG1 rescues defective trafficking of Na(v)1.5 mutations in Brugada syndrome and sick sinus syndrome.
23420830
2013
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Hereditary bundle branch system defect
0.980
GeneticVariation
UNIPROT
Type of SCN5A mutation determines clinical severity and degree of conduction slowing in loss-of-function sodium channelopathies.
19251209
2009
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Hereditary bundle branch system defect
0.980
GeneticVariation
UNIPROT
A common SCN5A polymorphism modulates the biophysical effects of an SCN5A mutation.
12569159
2003
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Hereditary bundle branch system defect
0.980
GeneticVariation
UNIPROT
Compound heterozygosity for mutations (W156X and R225W) in SCN5A associated with severe cardiac conduction disturbances and degenerative changes in the conduction system.
12574143
2003
×
Entrez Id:
6331
Gene Symbol:
SCN5A
SCN5A
Hereditary bundle branch system defect
0.980
GeneticVariation
UNIPROT
Clinical, genetic, and biophysical characterization of SCN5A mutations associated with atrioventricular conduction block.
11804990
2002