×
Entrez Id:
3164
Gene Symbol:
NR4A1
NR4A1
Malignant neoplasm of pancreas
0.350
AlteredExpression
BEFREE
1,1-Bis(3'-indolyl)-1-(p-anisyl)methane (DIM-C-pPhOCH3) activates the orphan receptor nerve growth factor-induced Balpha (Nur77 ) in cancer cells, and in this study, DIM-C-pPhOCH3 decreased Panc1 pancreatic cancer cell survival and arrested cells in G0-G1.
19584258
2009
×
Entrez Id:
887
Gene Symbol:
CCKBR
CCKBR
Malignant neoplasm of pancreas
0.100
GeneticVariation
BEFREE
10, 689-694) have identified a splice variant of CCK2R , called CCK2i4svR, that is expressed in human colorectal and pancreatic cancers but not by cells of the adjacent nonmalignant tissue.
15292208
2004
×
Entrez Id:
10333
Gene Symbol:
TLR6
TLR6
Malignant neoplasm of pancreas
0.010
GeneticVariation
BEFREE
18 SNPs in 14 candidate genes (CSF2, DENND1B, DPP10, FLG, IL13, IL13RA2, LRP1B, NOD1, NPSR1, ORMDL3, RORA, STAT4, TLR6 , TRA) were significantly associated with pancreas cancer risk.
25945796
2015
×
Entrez Id:
6955
Gene Symbol:
TRA
TRA
Malignant neoplasm of pancreas
0.040
GeneticVariation
BEFREE
18 SNPs in 14 candidate genes (CSF2, DENND1B, DPP10, FLG, IL13, IL13RA2, LRP1B, NOD1, NPSR1, ORMDL3, RORA, STAT4, TLR6, TRA ) were significantly associated with pancreas cancer risk.
25945796
2015
×
Entrez Id:
573
Gene Symbol:
BAG1
BAG1
Malignant neoplasm of pancreas
0.020
Biomarker
BEFREE
4-HAP also reduced liver metastases in human pancreatic cancer -bearing nude mice.
31358530
2019
×
Entrez Id:
6294
Gene Symbol:
SAFB
SAFB
Malignant neoplasm of pancreas
0.010
Biomarker
BEFREE
4-HAP also reduced liver metastases in human pancreatic cancer -bearing nude mice.
31358530
2019
×
Entrez Id:
5915
Gene Symbol:
RARB
RARB
Malignant neoplasm of pancreas
0.010
Biomarker
BEFREE
4-HAP also reduced liver metastases in human pancreatic cancer -bearing nude mice.
31358530
2019
×
Entrez Id:
10313
Gene Symbol:
RTN3
RTN3
Malignant neoplasm of pancreas
0.010
Biomarker
BEFREE
4-HAP also reduced liver metastases in human pancreatic cancer -bearing nude mice.
31358530
2019
×
Entrez Id:
4524
Gene Symbol:
MTHFR
MTHFR
Malignant neoplasm of pancreas
0.090
GeneticVariation
BEFREE
5,10-Methylenetetrahydrofolate reductase polymorphisms and the risk of pancreatic cancer .
15941958
2005
×
Entrez Id:
6581
Gene Symbol:
SLC22A3
SLC22A3
Malignant neoplasm of pancreas
0.040
Biomarker
BEFREE
5-FU resistant EMT -like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin.
29258566
2017
×
Entrez Id:
3702
Gene Symbol:
ITK
ITK
Malignant neoplasm of pancreas
0.020
Biomarker
BEFREE
5-FU resistant EMT -like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin.
29258566
2017
×
Entrez Id:
2022
Gene Symbol:
ENG
ENG
Malignant neoplasm of pancreas
0.020
Biomarker
BEFREE
5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin -targeting immunotoxin CD105-saporin.
29258566
2017
×
Entrez Id:
23650
Gene Symbol:
TRIM29
TRIM29
Malignant neoplasm of pancreas
0.030
Biomarker
BEFREE
: TRIM29 (tripartite motif-containing protein 29 ) is a TRIM family protein that has been implicated in breast, colorectal, and pancreatic cancers .
30389700
2018
×
Entrez Id:
50852
Gene Symbol:
TRAT1
TRAT1
Malignant neoplasm of pancreas
0.010
Biomarker
BEFREE
: TRIM29 (tripartite motif-containing protein 29) is a TRIM family protein that has been implicated in breast, colorectal, and pancreatic cancers .
30389700
2018
×
Entrez Id:
6382
Gene Symbol:
SDC1
SDC1
Malignant neoplasm of pancreas
0.040
AlteredExpression
BEFREE
Pancreatic cancer cell lines expressed syndecan-1 mRNA and protein at variable levels.
10962434
2000
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Malignant neoplasm of pancreas
0.600
GeneticVariation
BEFREE
Pancreatic cancer exhibits a high frequency of K-ras gene mutations; however, it is not known whether DOC-2 expression is altered in these tumors.
11406647
2001
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
Malignant neoplasm of pancreas
0.800
AlteredExpression
BEFREE
Pancreatic cancer is particularly resistant to apoptosis by antineoplastic agents, which is partly attributable to the lack of functional p53 .
11585734
2001
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
Malignant neoplasm of pancreas
0.400
Biomarker
BEFREE
Pancreatic cancer cells are susceptible to antiproliferative effects of cytokines such as tumor necrosis factor-alpha (TNF-alpha ).
11854621
2002
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
Malignant neoplasm of pancreas
0.400
AlteredExpression
BEFREE
Pancreatic cancer is no exception; MMP-2 and MMP-9 show high levels of expression in clinical and experimental models.
12167581
2002
×
Entrez Id:
4318
Gene Symbol:
MMP9
MMP9
Malignant neoplasm of pancreas
0.400
AlteredExpression
BEFREE
Pancreatic cancer is no exception; MMP-2 and MMP-9 show high levels of expression in clinical and experimental models.
12167581
2002
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of pancreas
0.600
GeneticVariation
BEFREE
Pancreatic cancer is seen in some breast cancer families with BRCA1 and BRCA2 mutations.
12670518
2003
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Malignant neoplasm of pancreas
0.800
GeneticVariation
BEFREE
Pancreatic cancer is seen in some breast cancer families with BRCA1 and BRCA2 mutations.
12670518
2003
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Malignant neoplasm of pancreas
0.600
Biomarker
BEFREE
Pancreatic cancer cell radiation survival and prenyltransferase inhibition: the role of K-Ras .
16166322
2005
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Malignant neoplasm of pancreas
0.600
GeneticVariation
BEFREE
Pancreatic cancer is usually initiated by mutation of KRAS and aberrant expression of SHH.
16367914
2006
×
Entrez Id:
6469
Gene Symbol:
SHH
SHH
Malignant neoplasm of pancreas
0.060
AlteredExpression
BEFREE
Pancreatic cancer is usually initiated by mutation of KRAS and aberrant expression of SHH .
16367914
2006