Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2875
Gene Symbol: GPT
GPT
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Biomarker CTD_human Gene expression profiles of hepatic cell-type specific marker genes in progression of liver fibrosis. 17072980

2006

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Biomarker CTD_human Ablation of primary afferent neurons by neonatal capsaicin treatment reduces the susceptibility of the portal hypertensive gastric mucosa to ethanol-induced injury in cirrhotic rats. 18555214

2008

Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Biomarker CTD_human Systems level analysis and identification of pathways and networks associated with liver fibrosis. 25380136

2014

Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Biomarker CTD_human Influence of leptin in the development of hepatic fibrosis produced in mice by Schistosoma mansoni infection and by chronic carbon tetrachloride administration. 12586293

2003

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Biomarker CTD_human Role of NLRC5 in progression and reversal of hepatic fibrosis. 26806094

2016

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Therapeutic CTD_human Ribozymes against TGFbeta1 reverse character of activated hepatic stellate cells in vitro and inhibit liver fibrosis in rats. 15772939

2005

Entrez Id: 100506742
Gene Symbol: CASP12
CASP12
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Biomarker CTD_human Systems level analysis and identification of pathways and networks associated with liver fibrosis. 25380136

2014

Entrez Id: 3586
Gene Symbol: IL10
IL10
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Therapeutic CTD_human Electroporative interleukin-10 gene transfer ameliorates carbon tetrachloride-induced murine liver fibrosis by MMP and TIMP modulation. 16539848

2006

Entrez Id: 1278
Gene Symbol: COL1A2
COL1A2
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Biomarker CTD_human Systems level analysis and identification of pathways and networks associated with liver fibrosis. 25380136

2014

Entrez Id: 3694
Gene Symbol: ITGB6
ITGB6
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Biomarker CTD_human Integrin alphavbeta6 is a marker of the progression of biliary and portal liver fibrosis and a novel target for antifibrotic therapies. 18221819

2008

Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Therapeutic CTD_human Inhibition of inducible nitric oxide synthase activity prevents liver recovery in rat thioacetamide-induced fibrosis reversal. 18380797

2008

Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Biomarker CTD_human rAAV-mediated stable expression of heme oxygenase-1 in stellate cells: a new approach to attenuate liver fibrosis in rats. 16025519

2005

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Biomarker CTD_human Influence of leptin in the development of hepatic fibrosis produced in mice by Schistosoma mansoni infection and by chronic carbon tetrachloride administration. 12586293

2003

Entrez Id: 5321
Gene Symbol: PLA2G4A
PLA2G4A
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Biomarker CTD_human Systems level analysis and identification of pathways and networks associated with liver fibrosis. 25380136

2014

Entrez Id: 3586
Gene Symbol: IL10
IL10
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Therapeutic CTD_human Antifibrotic effects of interleukin-10 on experimental hepatic fibrosis. 18251166

2008

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Biomarker CTD_human Disruption of the FasL/Fas axis protects against inflammation-derived tumorigenesis in chronic liver disease. 30737368

2019

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Therapeutic CTD_human Editor's Highlight: Modeling Compound-Induced Fibrogenesis In Vitro Using Three-Dimensional Bioprinted Human Liver Tissues. 27605418

2016

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Biomarker CTD_human Systems level analysis and identification of pathways and networks associated with liver fibrosis. 25380136

2014

Entrez Id: 1373
Gene Symbol: CPS1
CPS1
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Biomarker CTD_human Identification of fibrosis-relevant proteins using DIGE (difference in gel electrophoresis) in different models of hepatic fibrosis. 15650968

2005

Entrez Id: 133
Gene Symbol: ADM
ADM
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Biomarker CTD_human Adrenomedullin contributes to vascular hyporeactivity in cirrhotic rats with ascites via a release of nitric oxide. 15370692

2004

Entrez Id: 6678
Gene Symbol: SPARC
SPARC
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Therapeutic CTD_human Systems level analysis and identification of pathways and networks associated with liver fibrosis. 25380136

2014

Entrez Id: 4322
Gene Symbol: MMP13
MMP13
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Therapeutic CTD_human Scar-associated macrophages are a major source of hepatic matrix metalloproteinase-13 and facilitate the resolution of murine hepatic fibrosis. 17404313

2007

Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Therapeutic CTD_human Combination gene therapy of HGF and truncated type II TGF-beta receptor for rat liver cirrhosis after partial hepatectomy. 16627068

2006

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Biomarker CTD_human Neutral endopeptidase (EC 3.4.24.11) in cirrhotic liver: a new target to treat portal hypertension? 16085334

2005

Entrez Id: 5009
Gene Symbol: OTC
OTC
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.500 Biomarker CTD_human Systems level analysis and identification of pathways and networks associated with liver fibrosis. 25380136

2014