×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Infertility, treatment of infertility, and the risk of breast cancer among women with BRCA1 and BRCA2 mutations: a case-control study.
18509731 2008
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
CausalMutation
CLINVAR
Nonsense-mediated mRNA decay: terminating erroneous gene expression.
15145354 2004
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
BRCA1 and BRCA2 sequence variants in Chinese breast cancer families.
12442274 2002
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
Biomarker
BEFREE
Inconsistent results have been demonstrated for prognostic associations of BRCA2 -associated breast tumors .
10550164 1999
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
Biomarker
BEFREE
Molecular analysis of BRCA1 and BRCA2 genes by next generation sequencing and ultrastructural aspects of breast tumor tissue.
28730229 2017
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Understanding genetic analysis for breast cancer and its implications for plastic surgery.
19083511 2009
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
GeneticVariation
BEFREE
We found two primary breast tumors from BRCA2 mutation carriers, four sporadic primary breast tumors, and four sporadic primary ovarian tumors showed hypermethylation of the core promoter region of PALB2.
18281473 2008
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
GeneticVariation
BEFREE
To elucidate a possible role of BRCA2 and RB1 in sporadic breast tumorigenesis, allelic imbalance (AI) at 13q loci was examined in 78 primary sporadic breast tumors .AI was found in 52-63% of tumors.
8616837 1996
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
Biomarker
CTD_human
A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer.
28825726 2017
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Survival in prospectively ascertained familial breast cancer: analysis of a series stratified by tumour characteristics, BRCA mutations and oophorectomy.
12237897 2002
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
GeneticVariation
BEFREE
Furthermore, BRCA1 and BRCA2 mutated breast tumors differ from sporadic tumors in respect to histological phenotype.
10652564 2000
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Identification and evaluation of 55 genetic variations in the BRCA1 and the BRCA2 genes of patients from 50 Japanese breast cancer families.
15168169 2004
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
GeneticVariation
BEFREE
We found a strong association between the basal-like subtype and BRCA1-mutated breast tumors and the luminal B subtype and BRCA2 -mutated breast tumors .
22706203 2012
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
Biomarker
BEFREE
From 10 studies, including this one, 83% of BRCA1 breast tumors were ER-negative, whereas 76% of BRCA2 breast tumors were ER-positive.
11710890 2001
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Use of expression data and the CGEMS genome-wide breast cancer association study to identify genes that may modify risk in BRCA1/2 mutation carriers.
18095154 2008
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
BRCA mutations, molecular markers, and clinical variables in early-onset breast cancer: a population-based study.
17257844 2007
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
GeneticVariation
BEFREE
Chromosome imbalance at the 3p14 region in human breast tumours : high frequency in patients with inherited predisposition due to BRCA2 .
9624249 1998
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
Biomarker
LHGDN
[Analysis of BRCA2 gene mutations among familial and/or early-onset breast cancer patients in eastern Shandong of China].
18393245 2008
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
GeneticVariation
BEFREE
High frequency of allelic loss at the BRCA2 locus has been reported in sporadic breast tumors , but somatic mutations of BRCA2 are very rare.
11948477 2002
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
GeneticVariation
CLINVAR
Prevalence and Prognostic Role of BRCA1/2 Variants in Unselected Chinese Breast Cancer Patients.
27257965 2016
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
GeneticVariation
BEFREE
With respect to clinical-pathological characteristic, BRCA1/BRCA2 mutation carriers showed earlier onset age of breast tumour and higher risk of developing contra lateral breast cancer than non-informative cases.
28477318 2017
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Prevalence of BRCA1 and BRCA2 mutations in breast cancer patients from Brazil.
17063270 2007
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
BRCA1 and BRCA2 mutations as prognostic factors in bilateral breast cancer patients.
15319244 2004
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Use of association studies to define genetic modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers.
18283561 2008
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Mammary Neoplasms
0.500
GeneticVariation
BEFREE
We found that breast tumors from BRCA1 and BRCA2 mutation carriers display characteristic RNA expression patterns, allowing them to be distinguished from sporadic tumors.
23704984 2013