×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden).
10956390
2000
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
CDKN2A germ-line mutations in individuals with multiple cutaneous melanomas.
11156381
2000
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
Multiple primary tumors as an indicator for p16INK4a germline mutations in pancreatic cancer patients?
11075991
2000
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
Gene-covariate interaction between dysplastic nevi and the CDKN2A gene in American melanoma-prone families.
11008905
2000
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
Haplotype analysis and age estimation of the 113insR CDKN2A founder mutation in Swedish melanoma families.
11319798
2001
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
CDKN2A germline splicing mutation affecting both p16(ink4) and p14(arf) RNA processing in a melanoma/neurofibroma kindred.
11433531
2001
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
Mutations in the INK4a/ARF melanoma susceptibility locus functionally impair p14ARF.
11518711
2001
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
Functional impairment of melanoma-associated p16(INK4a) mutants in melanoma cells despite retention of cyclin-dependent kinase 4 binding.
11595726
2001
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
CDKN2A and CDK4 mutation analysis in Italian melanoma-prone families: functional characterization of a novel CDKN2A germ line mutation.
11556834
2001
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
CDKN2A and CDK4 mutation analysis in Italian melanoma-prone families: functional characterization of a novel CDKN2A germ line mutation.
11556834
2001
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
A common founder for the V126D CDKN2A mutation in seven North American melanoma-prone families.
11506491
2001
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
Validation of denaturing high performance liquid chromatography as a rapid detection method for the identification of human INK4A gene mutations.
11687599
2001
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
Multiple primary melanoma revisited.
12001124
2002
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
Phenotypic variation in eight extended CDKN2A germline mutation familial atypical multiple mole melanoma-pancreatic carcinoma-prone families: the familial atypical mole melanoma-pancreatic carcinoma syndrome.
11815963
2002
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
Phenotypic variation in eight extended CDKN2A germline mutation familial atypical multiple mole melanoma-pancreatic carcinoma-prone families: the familial atypical mole melanoma-pancreatic carcinoma syndrome.
11815963
2002
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
Geographical variation in the penetrance of CDKN2A mutations for melanoma.
12072543
2002
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
Geographical variation in the penetrance of CDKN2A mutations for melanoma.
12072543
2002
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
CDKN2A germline mutations in familial pancreatic cancer.
12454511
2002
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
Hereditary p16-Leiden mutation in a patient with multiple head and neck tumors.
12549483
2003
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
A single Mediterranean, possibly Jewish, origin for the Val59Gly CDKN2A mutation in four melanoma-prone families.
12700603
2003
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
Germline splicing mutations of CDKN2A predispose to melanoma.
14508519
2003
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
Identification of a splice acceptor site mutation in p16INK4A/p14ARF within a breast cancer, melanoma, neurofibroma prone kindred.
12920094
2003
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
CDKN2A point mutations D153spl(c.457G>T) and IVS2+1G>T result in aberrant splice products affecting both p16INK4a and p14ARF.
12853981
2003
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
Germline splicing mutations of CDKN2A predispose to melanoma.
14508519
2003
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
Estimating the relative risk of developing melanoma in INK4A carriers.
15075790
2004