×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
CausalMutation
CLINVAR
Hypertrophic cardiomyopathy--molecular genetic analysis of exons 9 and 11 of the TNNT2 gene in Czech patients.
16538283 2006
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
CausalMutation
CLINVAR
Phenotypic differences between electrocardiographic and echocardiographic determination of hypertrophic cardiomyopathy in genetically affected subjects.
16115294 2005
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
CausalMutation
CLINVAR
Dilated cardiomyopathy mutations in three thin filament regulatory proteins result in a common functional phenotype.
15923195 2005
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
CausalMutation
CLINVAR
Characterization of troponin T dilated cardiomyopathy mutations in the fetal troponin isoform.
15623536 2005
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
CausalMutation
CLINVAR
Mutation screening in dilated cardiomyopathy: prominent role of the beta myosin heavy chain gene.
15769782 2005
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
CausalMutation
CLINVAR
Mutations profile in Chinese patients with hypertrophic cardiomyopathy.
15563892 2005
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
CausalMutation
CLINVAR
Changes in the chemical and dynamic properties of cardiac troponin T cause discrete cardiomyopathies in transgenic mice.
16326803 2005
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
CausalMutation
CLINVAR
Familial hypertrophic cardiomyopathy mutations from different functional regions of troponin T result in different effects on the pH and Ca2+ sensitivity of cardiac muscle contraction.
14722098 2004
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
GeneticVariation
CLINVAR
Familial hypertrophic cardiomyopathy mutations from different functional regions of troponin T result in different effects on the pH and Ca2+ sensitivity of cardiac muscle contraction.
14722098 2004
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
CausalMutation
CLINVAR
The Delta 14 mutation of human cardiac troponin T enhances ATPase activity and alters the cooperative binding of S1-ADP to regulated actin.
15568820 2004
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
GeneticVariation
CLINVAR
Inherited cardiomyopathies as a troponin disease.
15631686 2004
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
GeneticVariation
CLINVAR
Prevalence and spectrum of thin filament mutations in an outpatient referral population with hypertrophic cardiomyopathy.
12860912 2003
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
CausalMutation
CLINVAR
Cardiac troponin T mutation R141W found in dilated cardiomyopathy stabilizes the troponin T-tropomyosin interaction and causes a Ca2+ desensitization.
14654368 2003
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
CausalMutation
CLINVAR
Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy.
12707239 2003
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
CausalMutation
CLINVAR
Comparison of fluorescent SSCP and denaturing HPLC analysis with direct sequencing for mutation screening in hypertrophic cardiomyopathy.
12746413 2003
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
CausalMutation
CLINVAR
Prevalence and clinical profile of troponin T mutations among patients with hypertrophic cardiomyopathy in tuscany.
14636924 2003
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
CausalMutation
CLINVAR
Autopsy findings in siblings with hypertrophic cardiomyopathy caused by Arg92Trp mutation in the cardiac troponin T gene showing dilated cardiomyopathy-like features.
14640471 2003
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
GeneticVariation
CLINVAR
Prevalence and clinical profile of troponin T mutations among patients with hypertrophic cardiomyopathy in tuscany.
14636924 2003
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
GeneticVariation
CLINVAR
Cardiac troponin T mutation R141W found in dilated cardiomyopathy stabilizes the troponin T-tropomyosin interaction and causes a Ca2+ desensitization.
14654368 2003
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
GeneticVariation
CLINVAR
Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy.
12707239 2003
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
CausalMutation
CLINVAR
Different functional properties of troponin T mutants that cause dilated cardiomyopathy.
12923187 2003
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
CausalMutation
CLINVAR
Prevalence and spectrum of thin filament mutations in an outpatient referral population with hypertrophic cardiomyopathy.
12860912 2003
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
CausalMutation
CLINVAR
Prevalence and age-dependence of malignant mutations in the beta-myosin heavy chain and troponin T genes in hypertrophic cardiomyopathy: a comprehensive outpatient perspective.
12084606 2002
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
CausalMutation
CLINVAR
Low-density DNA microarrays are versatile tools to screen for known mutations in hypertrophic cardiomyopathy.
11968089 2002
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
Hypertrophic Cardiomyopathy
0.800
GeneticVariation
CLINVAR
"Prevalence and severity of ""benign"" mutations in the beta-myosin heavy chain, cardiac troponin T, and alpha-tropomyosin genes in hypertrophic cardiomyopathy."
12473556 2002