rs3087243
|
|
Rheumatoid Arthritis
|
|
0.850 |
GeneticVariation
|
BEFREE |
We studied RA risk associated with PTPN22 (rs2476601), PADI-4 (rs2240340), and CTLA-4 (rs3087243) in the Nurses' Health Study (NHS) and NHSII.
|
18462498 |
2008 |
rs3087243
|
|
Rheumatoid Arthritis
|
|
0.850 |
GeneticVariation
|
BEFREE |
Markers associated with RA in populations of European ancestry (rs3087243 [+60C/T] and rs231775 [+49A/G]) were not replicated in African Americans.
|
19300490 |
2009 |
rs3087243
|
|
Rheumatoid Arthritis
|
G |
0.850 |
GeneticVariation
|
GWASCAT |
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.
|
20453842 |
2010 |
rs3087243
|
|
Rheumatoid Arthritis
|
G |
0.850 |
GeneticVariation
|
GWASDB |
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.
|
20453842 |
2010 |
rs3087243
|
|
Rheumatoid Arthritis
|
|
0.850 |
GeneticVariation
|
BEFREE |
Eight markers (ie, rs1160542 (AFF3), rs1678542 (KIF5A), rs2476601 (PTPN22), rs3087243 (CTLA4), rs4810485 (CD40), rs5029937 (6q23), rs10760130 (TRAF1/C5) and rs7574865 (STAT4)) were significantly associated with RA by meta-analysis.
|
20498205 |
2010 |
rs3087243
|
|
Rheumatoid Arthritis
|
|
0.850 |
GeneticVariation
|
GWASDB |
Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.
|
22446963 |
2012 |
rs3087243
|
|
Rheumatoid Arthritis
|
|
0.850 |
GeneticVariation
|
GWASCAT |
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
|
23143596 |
2012 |
rs3087243
|
|
Rheumatoid Arthritis
|
|
0.850 |
GeneticVariation
|
GWASDB |
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
|
23143596 |
2012 |
rs3087243
|
|
Rheumatoid Arthritis
|
|
0.850 |
GeneticVariation
|
BEFREE |
In conclusion, our results suggest that the -319C/+49G/CT60G haplotype of CTLA-4 gene is a genetic marker of susceptibility to RA in Western Mexico, whereas the rs3087243 SNP confers protection against this disease.
|
23703660 |
2013 |
rs3087243
|
|
Rheumatoid Arthritis
|
G |
0.850 |
GeneticVariation
|
GWASCAT |
Genetics of rheumatoid arthritis contributes to biology and drug discovery.
|
24390342 |
2014 |
rs3087243
|
|
Rheumatoid Arthritis
|
G |
0.850 |
GeneticVariation
|
GWASDB |
Genetics of rheumatoid arthritis contributes to biology and drug discovery.
|
24390342 |
2014 |
rs3087243
|
|
Rheumatoid Arthritis
|
G |
0.850 |
GeneticVariation
|
GWASCAT |
High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci.
|
24532676 |
2015 |
rs3087243
|
|
Rheumatoid Arthritis
|
|
0.850 |
GeneticVariation
|
BEFREE |
The results of our study suggest no significant association between CD28 rs1980422, CCL5 rs2107538, CTLA-4 exon 1 +49A>G rs231775 and rs3087243 gene polymorphisms and RA in the Polish population.
|
27988812 |
2017 |
rs3087243
|
|
Rheumatoid Arthritis
|
A |
0.850 |
GeneticVariation
|
GWASCAT |
Genetic influences on susceptibility to rheumatoid arthritis in African-Americans.
|
30423114 |
2019 |