|
rs9349379
|
|
Calcification of coronary artery
|
A |
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide significant associations with CAC for SNPs on chromosome 9p21 near CDKN2A and CDKN2B (top SNP: rs1333049; P=7.58×10(-19)) and 6p24 (top SNP: rs9349379, within the PHACTR1 gene; P=2.65×10(-11)) replicated for CAC and for MI.
|
22144573 |
2011 |
|
rs9349379
|
|
Calcification of coronary artery
|
|
0.800 |
GeneticVariation
|
GWASDB |
The second strongest association with CAC was with rs9349379 in the phosphatase and actin regulator 1 gene, PHACTR1, (Beta=0.30; 95% CI=0.22-0.40; p=4.67x10-11).
|
23394302 |
2013 |
|
rs749924
|
|
Calcification of coronary artery
|
T |
0.800 |
GeneticVariation
|
GWASDB |
Genetics of coronary artery calcification among African Americans, a meta-analysis.
|
23870195 |
2013 |
|
rs741013
|
|
Calcification of coronary artery
|
A |
0.800 |
GeneticVariation
|
GWASDB |
Genetics of coronary artery calcification among African Americans, a meta-analysis.
|
23870195 |
2013 |
|
rs7092929
|
|
Calcification of coronary artery
|
A |
0.800 |
GeneticVariation
|
GWASDB |
Genetics of coronary artery calcification among African Americans, a meta-analysis.
|
23870195 |
2013 |
|
rs3809346
|
|
Calcification of coronary artery
|
A |
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.
|
22144573 |
2011 |
|
rs2390582
|
|
Calcification of coronary artery
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study.
|
17903303 |
2007 |
|
rs1537370
|
|
Calcification of coronary artery
|
|
0.800 |
GeneticVariation
|
GWASDB |
Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study.
|
23394302 |
2013 |
|
rs1537370
|
|
Calcification of coronary artery
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.
|
22144573 |
2011 |
|
rs1537370
|
|
Calcification of coronary artery
|
T |
0.800 |
GeneticVariation
|
GWASDB |
The 9p21 locus was significantly associated with coronary artery calcification (rs1537370, P = 2.3 × 10(-11)).
|
23561647 |
2013 |
|
rs1333049
|
|
Calcification of coronary artery
|
|
0.800 |
GeneticVariation
|
GWASDB |
Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study.
|
23394302 |
2013 |
|
rs1333049
|
|
Calcification of coronary artery
|
C |
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide significant associations with CAC for SNPs on chromosome 9p21 near CDKN2A and CDKN2B (top SNP: rs1333049; P=7.58×10(-19)) and 6p24 (top SNP: rs9349379, within the PHACTR1 gene; P=2.65×10(-11)) replicated for CAC and for MI.
|
22144573 |
2011 |
|
rs10502575
|
|
Calcification of coronary artery
|
A |
0.800 |
GeneticVariation
|
GWASDB |
Genetics of coronary artery calcification among African Americans, a meta-analysis.
|
23870195 |
2013 |
|
rs9632885
|
|
Calcification of coronary artery
|
|
0.700 |
GeneticVariation
|
GWASDB |
Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study.
|
23394302 |
2013 |
|
rs9632884
|
|
Calcification of coronary artery
|
|
0.700 |
GeneticVariation
|
GWASDB |
Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study.
|
23394302 |
2013 |
|
rs9632884
|
|
Calcification of coronary artery
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.
|
22144573 |
2011 |
|
rs944801
|
|
Calcification of coronary artery
|
|
0.700 |
GeneticVariation
|
GWASDB |
Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study.
|
23394302 |
2013 |
|
rs944801
|
|
Calcification of coronary artery
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.
|
22144573 |
2011 |
|
rs944799
|
|
Calcification of coronary artery
|
|
0.700 |
GeneticVariation
|
GWASDB |
Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study.
|
23394302 |
2013 |
|
rs944797
|
|
Calcification of coronary artery
|
|
0.700 |
GeneticVariation
|
GWASDB |
Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study.
|
23394302 |
2013 |
|
rs944797
|
|
Calcification of coronary artery
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.
|
22144573 |
2011 |
|
rs8181050
|
|
Calcification of coronary artery
|
|
0.700 |
GeneticVariation
|
GWASDB |
Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study.
|
23394302 |
2013 |
|
rs8181050
|
|
Calcification of coronary artery
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.
|
22144573 |
2011 |
|
rs8089491
|
|
Calcification of coronary artery
|
A |
0.700 |
GeneticVariation
|
GWASDB |
Genetics of coronary artery calcification among African Americans, a meta-analysis.
|
23870195 |
2013 |
|
rs7866783
|
|
Calcification of coronary artery
|
|
0.700 |
GeneticVariation
|
GWASDB |
Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study.
|
23394302 |
2013 |