|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
ACG clinical guideline: Genetic testing and management of hereditary gastrointestinal cancer syndromes.
|
25645574 |
2015 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Population-based molecular detection of hereditary nonpolyposis colorectal cancer.
|
10829038 |
2000 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Verification of the three-step model in assessing the pathogenicity of mismatch repair gene variants.
|
21120944 |
2011 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Functional analysis of human MutSalpha and MutSbeta complexes in yeast.
|
9889267 |
1999 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
American Society of Clinical Oncology Expert Statement: collection and use of a cancer family history for oncology providers.
|
24493721 |
2014 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
MSH2 missense mutations and HNPCC syndrome: pathogenicity assessment in a human expression system.
|
18781619 |
2008 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Practice parameters for the identification and testing of patients at risk for dominantly inherited colorectal cancer--supporting documentation.
|
11598466 |
2001 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Gene symbol: hMSH2. Disease: Hereditary nonpolyposis colorectal cancer.
|
15046096 |
2004 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Identification of concurrent germ-line mutations in hMSH2 and/or hMLH1 in Japanese hereditary nonpolyposis colorectal cancer kindreds.
|
9419403 |
1997 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Guidelines on genetic evaluation and management of Lynch syndrome: a consensus statement by the US Multi-Society Task Force on Colorectal Cancer.
|
25003300 |
2014 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Genetic cancer risk assessment and counseling: recommendations of the national society of genetic counselors.
|
15604628 |
2004 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0): a policy statement of the American College of Medical Genetics and Genomics.
|
27854360 |
2017 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
A practice guideline from the American College of Medical Genetics and Genomics and the National Society of Genetic Counselors: referral indications for cancer predisposition assessment.
|
25394175 |
2015 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Functional analysis of HNPCC-related missense mutations in MSH2.
|
18822302 |
2008 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
ACMG policy statement: updated recommendations regarding analysis and reporting of secondary findings in clinical genome-scale sequencing.
|
25356965 |
2015 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Informing family members of individuals with Lynch syndrome: a guideline for clinical geneticists.
|
23535968 |
2013 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
A novel missense germline mutation in exon 2 of the hMSH2 gene in a HNPCC family from Southern Italy.
|
15896463 |
2005 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants.
|
22102614 |
2012 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Mutational analysis of the hMSH2 gene reveals a three base pair deletion in a family predisposed to colorectal cancer development.
|
7874129 |
1994 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Lynch Syndrome: A Primer for Urologists and Panel Recommendations.
|
25711197 |
2015 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
A large fraction of unclassified variants of the mismatch repair genes MLH1 and MSH2 is associated with splicing defects.
|
18561205 |
2008 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
HNPCC mutations in hMSH2 result in reduced hMSH2-hMSH6 molecular switch functions.
|
12124176 |
2002 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Germline MSH2 and MLH1 mutational spectrum including large rearrangements in HNPCC families from Poland (update study).
|
16451135 |
2006 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Identification of individuals at risk for Lynch syndrome using targeted evaluations and genetic testing: National Society of Genetic Counselors and the Collaborative Group of the Americas on Inherited Colorectal Cancer joint practice guideline.
|
22167527 |
2012 |
|
rs63750571
|
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.700 |
GeneticVariation
|
UNIPROT |
Systematic analysis of hMSH2 and hMLH1 in young colon cancer patients and controls.
|
9718327 |
1998 |