Source: CLINVAR

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121434596
rs121434596
NRAS
CUI: C0349639
Disease: Juvenile Myelomonocytic Leukemia
Juvenile Myelomonocytic Leukemia 		T 0.810 CausalMutation CLINVAR

dbSNP: rs121434596
rs121434596
NRAS
CUI: C2674723
Disease: RAS-ASSOCIATED AUTOIMMUNE LEUKOPROLIFERATIVE DISORDER
RAS-ASSOCIATED AUTOIMMUNE LEUKOPROLIFERATIVE DISORDER 		T 0.800 CausalMutation CLINVAR

dbSNP: rs121434596
rs121434596
NRAS
CUI: C2750732
Disease: Noonan Syndrome 6
Noonan Syndrome 6 		T 0.700 CausalMutation CLINVAR

dbSNP: rs121434596
rs121434596
NRAS
CUI: C0025202
Disease: melanoma
melanoma 		T 0.700 CausalMutation CLINVAR BRAF and NRAS mutations in melanoma: potential relationships to clinical response to HSP90 inhibitors. 18375819

2008
dbSNP: rs121434596
rs121434596
NRAS
CUI: C0025202
Disease: melanoma
melanoma 		T 0.700 CausalMutation CLINVAR Combined targeting of MEK and PI3K/mTOR effector pathways is necessary to effectively inhibit NRAS mutant melanoma in vitro and in vivo. 23431193

2013
dbSNP: rs121434596
rs121434596
NRAS
CUI: C0025202
Disease: melanoma
melanoma 		A 0.700 CausalMutation CLINVAR Distinct sets of genetic alterations in melanoma. 16291983

2005
dbSNP: rs121434596
rs121434596
NRAS
CUI: C0025202
Disease: melanoma
melanoma 		G 0.700 CausalMutation CLINVAR Distinct sets of genetic alterations in melanoma. 16291983

2005
dbSNP: rs121434596
rs121434596
NRAS
CUI: C0025202
Disease: melanoma
melanoma 		T 0.700 CausalMutation CLINVAR Distinct sets of genetic alterations in melanoma. 16291983

2005
dbSNP: rs121434596
rs121434596
NRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs121434596
rs121434596
NRAS
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs121434596
rs121434596
NRAS
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs121434596
rs121434596
NRAS
CUI: C0279680
Disease: Transitional cell carcinoma of bladder
Transitional cell carcinoma of bladder 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs121434596
rs121434596
NRAS
CUI: C0025149
Disease: Medulloblastoma
Medulloblastoma 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs121434596
rs121434596
NRAS
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs121434596
rs121434596
NRAS
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs121434596
rs121434596
NRAS
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs121434596
rs121434596
NRAS
CUI: C3463824
Disease: MYELODYSPLASTIC SYNDROME
MYELODYSPLASTIC SYNDROME 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs121434596
rs121434596
NRAS
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs121434596
rs121434596
NRAS
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs121434596
rs121434596
NRAS
CUI: C4721532
Disease: Lymphoma, Non-Hodgkin, Familial
Lymphoma, Non-Hodgkin, Familial 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs121434596
rs121434596
NRAS
CUI: C4721532
Disease: Lymphoma, Non-Hodgkin, Familial
Lymphoma, Non-Hodgkin, Familial 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs121434596
rs121434596
NRAS
CUI: C3463824
Disease: MYELODYSPLASTIC SYNDROME
MYELODYSPLASTIC SYNDROME 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs121434596
rs121434596
NRAS
CUI: C0025149
Disease: Medulloblastoma
Medulloblastoma 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs121434596
rs121434596
NRAS
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs121434596
rs121434596
NRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016