|
rs11538209
|
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our data suggest that T29C TGFbeta1 gene polymorphism was associated to clinical characteristics suitable to recognize hypertensives with a higher severity of hypertension.
|
18821144 |
2008 |
|
rs11538209
|
|
Diabetic Nephropathy
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results suggest that TGF-beta1 T29C polymorphism is not associated with the progression of diabetic nephropathy.
|
11576951 |
2001 |
|
rs1162592300
|
|
Chronic kidney disease stage 5
|
|
0.010 |
GeneticVariation
|
BEFREE |
The -174G/C polymorphism of the IL-6 gene and the chemokine receptor CX3CR1 polymorphisms 249V/I and 280T/M were examined for their association with cardiovascular abnormalities in a cohort of 161 patients with end-stage renal disease (ESRD) treated by hemodialysis.
|
12846758 |
2003 |
|
rs1162592300
|
|
Kidney Failure, Chronic
|
|
0.010 |
GeneticVariation
|
BEFREE |
The -174G/C polymorphism of the IL-6 gene and the chemokine receptor CX3CR1 polymorphisms 249V/I and 280T/M were examined for their association with cardiovascular abnormalities in a cohort of 161 patients with end-stage renal disease (ESRD) treated by hemodialysis.
|
12846758 |
2003 |
|
rs1162592300
|
|
Cardiovascular Abnormalities
|
|
0.010 |
GeneticVariation
|
BEFREE |
The -174G/C polymorphism of the IL-6 gene and the chemokine receptor CX3CR1 polymorphisms 249V/I and 280T/M were examined for their association with cardiovascular abnormalities in a cohort of 161 patients with end-stage renal disease (ESRD) treated by hemodialysis.
|
12846758 |
2003 |
|
rs1171303257
|
|
Malignant Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
The genotype spectrum discriminated on this strip includes the high-risk, or cancer-associated, HPV genotypes 16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 55, 56, 58, 59, 68 (ME180), MM4 (W13B), MM7 (P291), and MM9 (P238A) and the low-risk, or non-cancer-associated, genotypes 6, 11, 40, 42, 53, 54, 57, 66, and MM8 (P155).
|
9738060 |
1998 |
|
rs1171303257
|
|
Primary malignant neoplasm
|
|
0.010 |
GeneticVariation
|
BEFREE |
The genotype spectrum discriminated on this strip includes the high-risk, or cancer-associated, HPV genotypes 16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 55, 56, 58, 59, 68 (ME180), MM4 (W13B), MM7 (P291), and MM9 (P238A) and the low-risk, or non-cancer-associated, genotypes 6, 11, 40, 42, 53, 54, 57, 66, and MM8 (P155).
|
9738060 |
1998 |
|
rs1241977606
|
|
Focal glomerulosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The R229Q variant is not associated with focal segmental glomerulosclerosis in the US population of African descent.
|
16481888 |
2006 |
|
rs1241977606
|
|
Childhood nephrotic syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
We calculated crude odds ratios and 95% confidence intervals of childhood nephrotic syndrome and focal segmental glomerulosclerosis associated with R229Q heterozygosity using data from five studies.
|
16481888 |
2006 |
|
rs1332629192
|
|
Diabetic Nephropathy
|
|
0.020 |
GeneticVariation
|
BEFREE |
The V16A polymorphism in SOD2 is associated with increased risk of diabetic nephropathy and cardiovascular disease in type 1 diabetes.
|
19834686 |
2009 |
|
rs1332629192
|
|
Diabetic Nephropathy
|
|
0.020 |
GeneticVariation
|
BEFREE |
The present study aimed to determine whether a valine/alanine polymorphism in MnSOD (V16A, rs4880), alone or in combination with smoking, can contribute to development of diabetic nephropathy in 1,510 Finnish and Swedish patients with type 1 diabetes.
|
17192491 |
2007 |
|
rs1332629192
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.020 |
GeneticVariation
|
BEFREE |
SOD2 gene Val16Ala polymorphism is associated with macroalbuminuria in Mexican type 2 diabetes patients: a comparative study and meta-analysis.
|
24119114 |
2013 |
|
rs1332629192
|
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.020 |
GeneticVariation
|
BEFREE |
The present study aimed to determine whether a valine/alanine polymorphism in MnSOD (V16A, rs4880), alone or in combination with smoking, can contribute to development of diabetic nephropathy in 1,510 Finnish and Swedish patients with type 1 diabetes.
|
17192491 |
2007 |
|
rs1332629192
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.020 |
GeneticVariation
|
BEFREE |
These results suggest that V16A polymorphism of Mn-SOD gene is not related to pathogenesis of diabetes but is associated with stages of albuminuria in Korean type 2 diabetes.
|
16324912 |
2006 |
|
rs1332629192
|
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.020 |
GeneticVariation
|
BEFREE |
The MnSOD V16A polymorphism is involved in the development of nephropathy caused by type 1 diabetes and seems to predict cardiovascular disease during follow-up.
|
19834686 |
2009 |
|
rs1332629192
|
|
Diabetes Mellitus
|
|
0.010 |
GeneticVariation
|
BEFREE |
These results suggest that V16A polymorphism of Mn-SOD gene is not related to pathogenesis of diabetes but is associated with stages of albuminuria in Korean type 2 diabetes.
|
16324912 |
2006 |
|
rs1332629192
|
|
Diabetes
|
|
0.010 |
GeneticVariation
|
BEFREE |
These results suggest that V16A polymorphism of Mn-SOD gene is not related to pathogenesis of diabetes but is associated with stages of albuminuria in Korean type 2 diabetes.
|
16324912 |
2006 |
|
rs1332629192
|
|
Kidney Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
The MnSOD V16A polymorphism is involved in the development of nephropathy caused by type 1 diabetes and seems to predict cardiovascular disease during follow-up.
|
19834686 |
2009 |
|
rs1332629192
|
|
Cardiovascular Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
The MnSOD V16A polymorphism is involved in the development of nephropathy caused by type 1 diabetes and seems to predict cardiovascular disease during follow-up.
|
19834686 |
2009 |
|
rs140421861
|
|
Diabetic Retinopathy
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our study suggests that the 936 C/T polymorphism of the VEGF gene may be an important factor determining plasma VEGF levels and that its polymorphism is related with diabetic retinopathy.
|
19796028 |
2009 |
|
rs370819889
|
|
Chronic kidney disease stage 5
|
|
0.010 |
GeneticVariation
|
BEFREE |
To evaluate the respective roles of residual glomerular filtration (by measuring a specific protein marker, cystatin C), genetic polymorphisms and nutritional status in tHcy blood levels in end-stage renal disease patients (ESRD) under hemodialysis and supplemented with folate, we measured tHcy, folate, vitamin B12 (B12), creatinine, cystatin C, albumin and C-reactive protein and determined the polymorphism of methylenetetrahydrofolate reductase (MTHFR) (C677T and A1289C) and of methionine synthase (MS) (A2756G) in 114 ESRD patients before hemodialysis and 76 control subjects.
|
11592445 |
2001 |
|
rs370819889
|
|
Kidney Failure, Chronic
|
|
0.010 |
GeneticVariation
|
BEFREE |
To evaluate the respective roles of residual glomerular filtration (by measuring a specific protein marker, cystatin C), genetic polymorphisms and nutritional status in tHcy blood levels in end-stage renal disease patients (ESRD) under hemodialysis and supplemented with folate, we measured tHcy, folate, vitamin B12 (B12), creatinine, cystatin C, albumin and C-reactive protein and determined the polymorphism of methylenetetrahydrofolate reductase (MTHFR) (C677T and A1289C) and of methionine synthase (MS) (A2756G) in 114 ESRD patients before hemodialysis and 76 control subjects.
|
11592445 |
2001 |
|
rs374651285
|
|
nervous system disorder
|
|
0.010 |
GeneticVariation
|
BEFREE |
Here, we investigated the potential of α-synuclein fibrils to induce neurological disease in TgM83<sup>+/-</sup> mice expressing the A53T mutant of human α-synuclein after oral or intravenous challenge and compared it to intraperitoneal and intracerebral challenge.
|
31230104 |
2019 |
|
rs534536101
|
|
Leukopenia
|
|
0.010 |
GeneticVariation
|
BEFREE |
The single nucleotide polymorphism (SNP) c.415C>T in exon 3 of <i>NUDT15</i> affects thiopurine-induced leukopenia in Asian patients with Crohn's disease.
|
29398872 |
2018 |
|
rs534536101
|
|
Crohn Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
The single nucleotide polymorphism (SNP) c.415C>T in exon 3 of <i>NUDT15</i> affects thiopurine-induced leukopenia in Asian patients with Crohn's disease.
|
29398872 |
2018 |