DisGeNET - a database of gene-disease associations

Source: GWASCAT

Gene: TET2 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs10010325

TET2 ; TET2-AS1

CUI:	C0005890
Disease:	Body Height

Body Height

0.700

GeneticVariation

GWASCAT

Hundreds of variants clustered in genomic loci and biological pathways affect human height.

20881960

2010

dbSNP:

rs9790517

TET2

CUI:	C0678222
Disease:	Breast Carcinoma

Breast Carcinoma

0.710

GeneticVariation

GWASCAT

Large-scale genotyping identifies 41 new loci associated with breast cancer risk.

23535729

2013

dbSNP:

rs6855629

TET2 ; TET2-AS1

CUI:	C0005890
Disease:	Body Height

Body Height

0.700

GeneticVariation

GWASCAT

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.

23563607

2013

dbSNP:

rs2726518

TET2 ; TET2-AS1

CUI:	C0026769
Disease:	Multiple Sclerosis

Multiple Sclerosis

0.700

GeneticVariation

GWASCAT

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.

24076602

2013

dbSNP:

rs4698934

TET2 ; TET2-AS1

CUI:	C0025202
Disease:	melanoma

melanoma

0.810

GeneticVariation

GWASCAT

The SNP rs4698934 was nominally significantly associated with melanoma risk.

24980573

2014

dbSNP:

rs9790517

TET2

CUI:	C0678222
Disease:	Breast Carcinoma

Breast Carcinoma

0.710

GeneticVariation

GWASCAT

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer.

25751625

2015

dbSNP:

rs2454206

TET2 ; TET2-AS1

CUI:	C0005890
Disease:	Body Height

Body Height

0.700

GeneticVariation

GWASCAT

Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.

25429064

2015

dbSNP:

rs2189234

TET2

CUI:	C0009324
Disease:	Ulcerative Colitis

Ulcerative Colitis

0.700

GeneticVariation

GWASCAT

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.

26192919

2015

dbSNP:

rs2189234

TET2

CUI:	C0021390
Disease:	Inflammatory Bowel Diseases

Inflammatory Bowel Diseases

0.700

GeneticVariation

GWASCAT

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.

26192919

2015

dbSNP:

rs2047409

TET2 ; TET2-AS1

CUI:	C0016529
Disease:	Forced expiratory volume function

Forced expiratory volume function

0.700

GeneticVariation

GWASCAT

Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank.

26423011

2015

dbSNP:

rs139887111

TET2 ; TET2-AS1

CUI:	C0016529
Disease:	Forced expiratory volume function

Forced expiratory volume function

0.700

GeneticVariation

GWASCAT

Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank.

26423011

2015

dbSNP:

rs10010325

TET2 ; TET2-AS1

CUI:	C0009324
Disease:	Ulcerative Colitis

Ulcerative Colitis

0.700

GeneticVariation

GWASCAT

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.

26192919

2015

dbSNP:

rs546941547

TET2 ; TET2-AS1

CUI:	C0200635
Disease:	Lymphocyte Count measurement

Lymphocyte Count measurement

0.700

GeneticVariation

GWASCAT

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

27863252

2016

dbSNP:

rs9790517

TET2

CUI:	C0678222
Disease:	Breast Carcinoma

Breast Carcinoma

0.710

GeneticVariation

GWASCAT

Association analysis identifies 65 new breast cancer risk loci.

29059683

2017

dbSNP:

rs62331150

TET2

CUI:	C0678222
Disease:	Breast Carcinoma

Breast Carcinoma

0.700

GeneticVariation

GWASCAT

Association analysis identifies 65 new breast cancer risk loci.

29059683

2017

dbSNP:

rs2726492

TET2 ; TET2-AS1

CUI:	C0678222
Disease:	Breast Carcinoma

Breast Carcinoma

0.700

GeneticVariation

GWASCAT

Association analysis identifies 65 new breast cancer risk loci.

29059683

2017

dbSNP:

rs2047409

TET2 ; TET2-AS1

CUI:	C0024117
Disease:	Chronic Obstructive Airway Disease

Chronic Obstructive Airway Disease

0.700

GeneticVariation

GWASCAT

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.

28166215

2017

dbSNP:

rs11726786

TET2 ; TET2-AS1

CUI:	C0021704
Disease:	Intelligence

Intelligence

0.700

GeneticVariation

GWASCAT

Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.

29186694

2017

dbSNP:

rs7683416

TET2 ; TET2-AS1

CUI:	C0596887
Disease:	mathematical ability

mathematical ability

0.700

GeneticVariation

GWASCAT

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.

30038396

2018

dbSNP:

rs7683416

TET2 ; TET2-AS1

CUI:	C0021704
Disease:	Intelligence

Intelligence

0.700

GeneticVariation

GWASCAT

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

29844566

2018

dbSNP:

rs2903385

TET2 ; TET2-AS1

CUI:	C0021704
Disease:	Intelligence

Intelligence

0.700

GeneticVariation

GWASCAT

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

29844566

2018

dbSNP:

rs2647249

TET2 ; TET2-AS1

CUI:	C0021704
Disease:	Intelligence

Intelligence

0.700

GeneticVariation

GWASCAT

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

29844566

2018

dbSNP:

rs2647249

TET2 ; TET2-AS1

CUI:	C0021704
Disease:	Intelligence

Intelligence

0.700

GeneticVariation

GWASCAT

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.

29942086

2018

dbSNP:

rs2454205

TET2 ; TET2-AS1

CUI:	C0021704
Disease:	Intelligence

Intelligence

0.700

GeneticVariation

GWASCAT

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.

29942086

2018

dbSNP:

rs1498126

TET2 ; TET2-AS1

CUI:	C0205682
Disease:	Waist-Hip Ratio

Waist-Hip Ratio

0.700

GeneticVariation

GWASCAT

Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors.

30575882

2018