DisGeNET - a database of gene-disease associations

Source: ALL

Disease: Renal Cell Carcinoma ×

Gene: TP53 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs1042522

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.020

GeneticVariation

BEFREE

Taken together, this is the first study to show that a variant genotype of p53 Arg(72)Pro or MDM2 SNP309 may modify the arsenic-related RCC risk even in a non-obvious arsenic exposure area.

21982800

2011

dbSNP:

rs1042522

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.020

GeneticVariation

BEFREE

Polymorphisms of p53 Arg(72)Pro and p21 Ser(31)Arg did not show significant association with RCC.

17634539

2007

dbSNP:

rs1057519977

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.700

GeneticVariation

CLINVAR

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

26619011

2016

dbSNP:

rs1057519978

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.700

GeneticVariation

CLINVAR

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

26619011

2016

dbSNP:

rs1057519978

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.700

GeneticVariation

CLINVAR

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

26619011

2016

dbSNP:

rs1057519978

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.700

GeneticVariation

CLINVAR

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

26619011

2016

dbSNP:

rs1057519983

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.700

GeneticVariation

CLINVAR

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

26619011

2016

dbSNP:

rs1057519992

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.700

GeneticVariation

CLINVAR

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

26619011

2016

dbSNP:

rs1057519992

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.700

GeneticVariation

CLINVAR

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

26619011

2016

dbSNP:

rs1057519999

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.700

GeneticVariation

CLINVAR

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

26619011

2016

dbSNP:

rs1057520001

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.010

GeneticVariation

BEFREE

Polymorphisms of p53 Arg(72)Pro and p21 Ser(31)Arg did not show significant association with RCC.

17634539

2007

dbSNP:

rs1057520002

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.700

GeneticVariation

CLINVAR

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

26619011

2016

dbSNP:

rs1057520002

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.700

GeneticVariation

CLINVAR

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

26619011

2016

dbSNP:

rs1057520003

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.700

GeneticVariation

CLINVAR

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

26619011

2016

dbSNP:

rs1057520007

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.700

GeneticVariation

CLINVAR

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

26619011

2016

dbSNP:

rs1057520007

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.700

GeneticVariation

CLINVAR

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

26619011

2016

dbSNP:

rs1057520007

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.700

GeneticVariation

CLINVAR

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

26619011

2016

dbSNP:

rs1131691014

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.020

GeneticVariation

BEFREE

Taken together, this is the first study to show that a variant genotype of p53 Arg(72)Pro or MDM2 SNP309 may modify the arsenic-related RCC risk even in a non-obvious arsenic exposure area.

21982800

2011

dbSNP:

rs1131691014

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.020

GeneticVariation

BEFREE

Polymorphisms of p53 Arg(72)Pro and p21 Ser(31)Arg did not show significant association with RCC.

17634539

2007

dbSNP:

rs121912657

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.700

GeneticVariation

CLINVAR

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

26619011

2016

dbSNP:

rs121912666

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.700

GeneticVariation

CLINVAR

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

26619011

2016

dbSNP:

rs121912666

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.700

GeneticVariation

CLINVAR

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

26619011

2016

dbSNP:

rs28934573

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.700

GeneticVariation

CLINVAR

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

26619011

2016

dbSNP:

rs28934573

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.700

GeneticVariation

CLINVAR

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

26619011

2016

dbSNP:

rs28934573

TP53

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.700

GeneticVariation

CLINVAR

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

26619011

2016