|
rs1057518897
|
|
Hypertensive disease
|
T |
0.700 |
CausalMutation
|
CLINVAR |
|
|
|
|
rs1057518856
|
|
Hypertensive disease
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
|
|
|
|
rs1057518797
|
|
Hypertensive disease
|
TAGGACG |
0.700 |
CausalMutation
|
CLINVAR |
|
|
|
|
rs104886142
|
|
Hypertensive disease
|
A |
0.700 |
CausalMutation
|
CLINVAR |
|
|
|
|
rs429358
|
|
Hypertensive disease
|
|
0.710 |
GeneticVariation
|
BEFREE |
<b>Aim:</b> To explore the association of APOE polymorphism (rs7412:526C>T and rs429358:388T>C) with glucose, lipid and serum uric acid (UA) metabolism in patients with hypertension or coronary heart disease (CHD).
|
31559922 |
2019 |
|
rs4588
|
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
<b>Objectives</b>: The vitamin D binding protein encoded by the <i>GC</i> gene contains two single nucleotide polymorphisms (rs4588 and rs7041) that have been associated with disease outcome, these include periodontitis coronary heart disease and hypertension.
|
31559882 |
2019 |
|
rs7041
|
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
<b>Objectives</b>: The vitamin D binding protein encoded by the <i>GC</i> gene contains two single nucleotide polymorphisms (rs4588 and rs7041) that have been associated with disease outcome, these include periodontitis coronary heart disease and hypertension.
|
31559882 |
2019 |
|
rs8259
|
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
<i>BSG</i> rs8259 TT genotype was associated with a decreased risk of CHF (OR = 0.83, 95% CI = 0.72-0.96, <i>p</i> = 0.010), especially in patients with hypertension (OR = 0.80, 95% CI = 0.68-0.95, <i>p</i> = 0.011) and coronary heart disease (OR = 0.81, 95% CI = 0.69-0.96, <i>p</i> = 0.013) after adjustment for multiple cardiovascular risk factors.
|
28230811 |
2017 |
|
rs1800775
|
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
(3) The rs1800775 polymorphism was associated with high fasting blood glucose levels and low high density lipoprotein cholesterol (HDL-C); rs3764261 and rs12149545 polymorphisms were associated with all components of MS except high blood pressure; rs711752 and rs708272 polymorphisms were associated with low HDL-C (all <i>p</i> < 0.05).
|
28629169 |
2017 |
|
rs3764261
|
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
(3) The rs1800775 polymorphism was associated with high fasting blood glucose levels and low high density lipoprotein cholesterol (HDL-C); rs3764261 and rs12149545 polymorphisms were associated with all components of MS except high blood pressure; rs711752 and rs708272 polymorphisms were associated with low HDL-C (all <i>p</i> < 0.05).
|
28629169 |
2017 |
|
rs12149545
|
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
(3) The rs1800775 polymorphism was associated with high fasting blood glucose levels and low high density lipoprotein cholesterol (HDL-C); rs3764261 and rs12149545 polymorphisms were associated with all components of MS except high blood pressure; rs711752 and rs708272 polymorphisms were associated with low HDL-C (all <i>p</i> < 0.05).
|
28629169 |
2017 |
|
rs711752
|
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
(3) The rs1800775 polymorphism was associated with high fasting blood glucose levels and low high density lipoprotein cholesterol (HDL-C); rs3764261 and rs12149545 polymorphisms were associated with all components of MS except high blood pressure; rs711752 and rs708272 polymorphisms were associated with low HDL-C (all <i>p</i> < 0.05).
|
28629169 |
2017 |
|
rs708272
|
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
(3) The rs1800775 polymorphism was associated with high fasting blood glucose levels and low high density lipoprotein cholesterol (HDL-C); rs3764261 and rs12149545 polymorphisms were associated with all components of MS except high blood pressure; rs711752 and rs708272 polymorphisms were associated with low HDL-C (all <i>p</i> < 0.05).
|
28629169 |
2017 |
|
rs2069837
|
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Hypertension significantly modified the association between rs2069837 polymorphisms and the risk of LOAD (pinteraction = 0.03).
|
22272811 |
2012 |
|
rs1799998
|
|
Hypertensive disease
|
|
0.040 |
GeneticVariation
|
BEFREE |
Hypertension association reached genome-wide significance for the two variants, specifically, P=7.3 × 10(-10) for AGT rs699 and P=3.9 × 10(-8) for CYP11B2 rs1799998.
|
22456346 |
2012 |
|
rs699
|
|
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Hypertension association reached genome-wide significance for the two variants, specifically, P=7.3 × 10(-10) for AGT rs699 and P=3.9 × 10(-8) for CYP11B2 rs1799998.
|
22456346 |
2012 |
|
rs17809012
|
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Hypertension stratification analyses showed that the GA genotype of rs17809012 was significantly associated with LAA stroke in the hypertensive group (adjusted OR=1.274, 95%CI=1.015-1.601).
|
28873081 |
2017 |
|
rs76425569
|
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Hypertension stratification analyses demonstrated that the GA/AA genotype of rs76425569 was significantly associated with lacunar stroke in the hypertensive group (adjusted OR = 1.316, 95% CI = 1.083-1.598, P = 0.006).
|
31214923 |
2019 |
|
rs4539
|
|
Hypertensive disease
|
|
0.050 |
GeneticVariation
|
BEFREE |
Lys(173)Arg and -344T/C variants of CYP11B2 in Japanese patients with low-renin hypertension.
|
10720581 |
2000 |
|
rs699
|
|
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
M235T polymorphism of AGT has been studied extensively in many populations including Japanese, and the results suggest a weak, but significant linkage with hypertension.
|
11128865 |
2000 |
|
rs1267969615
|
|
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
M235T polymorphism of AGT has been studied extensively in many populations including Japanese, and the results suggest a weak, but significant linkage with hypertension.
|
11128865 |
2000 |
|
rs699
|
|
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
M235T and T174M variants do not contribute to the increased risk of CHD or hypertension in the Indian population.
|
12938141 |
2003 |
|
rs1267969615
|
|
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
M235T and T174M variants do not contribute to the increased risk of CHD or hypertension in the Indian population.
|
12938141 |
2003 |
|
rs5479
|
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
C468A alone correlates significantly with hypertension (9%) and was identified only in 3% of control subjects (P < .05), whereas G534A was identified also in about 7% of normotensive subjects.
|
16109323 |
2005 |
|
rs699
|
|
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
M235T polymorphism of the angiotensinogen gene and insertion/deletion polymorphism of the angiotensin-1 converting enzyme gene in essential arterial hypertension in Caucasians.
|
17448297 |
2007 |