DisGeNET - a database of gene-disease associations

Source: CLINVAR

Disease: Colorectal Neoplasms ×

Variant: rs121913530 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs121913530

KRAS

CUI:	C0009404
Disease:	Colorectal Neoplasms

Colorectal Neoplasms

0.700

CausalMutation

CLINVAR

Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

25157968

2014

dbSNP:

rs121913530

KRAS

CUI:	C0009404
Disease:	Colorectal Neoplasms

Colorectal Neoplasms

0.700

CausalMutation

CLINVAR

Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer.

18316791

2008

dbSNP:

rs121913530

KRAS

CUI:	C0009404
Disease:	Colorectal Neoplasms

Colorectal Neoplasms

0.700

CausalMutation

CLINVAR

KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer.

16618717

2006

dbSNP:

rs121913530

KRAS

CUI:	C0009404
Disease:	Colorectal Neoplasms

Colorectal Neoplasms

0.700

CausalMutation

CLINVAR

Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer.

18316791

2008