|
rs113488022
|
|
Thyroid Nodule
|
|
0.100 |
GeneticVariation
|
BEFREE |
The application of BRAF(V600E) mutation analysis in FNA specimens is more effective for thyroid nodules with malignant US features as compared with nodules without malignant US features.
|
20187782 |
2010 |
|
rs113488022
|
|
Thyroid Nodule
|
|
0.100 |
GeneticVariation
|
BEFREE |
The application of BRAF(V600E) mutation analysis in US-guided FNAB can improve the diagnostic accuracy of thyroid nodules.
|
21707687 |
2011 |
|
rs113488022
|
|
Thyroid Nodule
|
|
0.100 |
GeneticVariation
|
BEFREE |
The BRAF(V600E) mutation analysis was a useful adjunctive diagnostic tool in the diagnosis of thyroid nodules with suspicious ultrasound features regardless of size.
|
23717622 |
2013 |
|
rs113488022
|
|
Thyroid Nodule
|
|
0.100 |
GeneticVariation
|
BEFREE |
The detection rate of the BRAF(V600E) mutation in thyroid nodules without suspicious US features was only 6.6 % (32/485).
|
24452872 |
2014 |
|
rs113488022
|
|
Thyroid Nodule
|
|
0.100 |
GeneticVariation
|
BEFREE |
The molecular tests on the thyroid nodule revealed the presence of BRAF-V600E mutation, but wild type BRAF in the ectopic tissue.
|
23200790 |
2013 |
|
rs113488022
|
|
Thyroid Nodule
|
|
0.100 |
GeneticVariation
|
BEFREE |
The preoperative knowledge of the V600E mutation status is fundamental to plan total thyroidectomy with certainty and should be part of the decision tree for the management of thyroid nodules.
|
26854757 |
2016 |
|
rs113488022
|
|
Thyroid Nodule
|
|
0.100 |
GeneticVariation
|
BEFREE |
The probability of PTC for thyroid nodules with intermediat</span>e-risk (IR) US and atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) FNAB was significantly dependent on BRAF V600E mutation status based on our prediction table (negative, 29.2% vs positive, 87.5%; P < 0.001).
|
26020381 |
2015 |
|
rs113488022
|
|
Thyroid Nodule
|
|
0.100 |
GeneticVariation
|
BEFREE |
These results indicate that BRAF(V600E) assessment by pyrosequencing is a reliable assay useful to refine inconclusive cytology of thyroid nodules also in the presence of concurrent HT.
|
23775008 |
2014 |
|
rs113488022
|
|
Thyroid Nodule
|
|
0.100 |
GeneticVariation
|
BEFREE |
To evaluate BRAF(V600E) mutation on consecutive fine-needle aspiration biopsy (FNAB) specimens in order to assess FNAB's usefulness in preoperative papillary thyroid carcinoma (PTC) diagnosis with the contemporaneous analysis of RET/PTC1 and RET/PTC3 rearrangements obtained from ex vivo thyroid nodules.
|
17727338 |
2007 |
|
rs113488022
|
|
Thyroid Nodule
|
|
0.100 |
GeneticVariation
|
BEFREE |
To evaluate the role of pre-operative detection of BRAF(V600E) mutation in the FNAB specimens of thyroid nodules in a BRAF(V600E) mutation-prevalent geographical area.
|
17054470 |
2006 |
|
rs113488022
|
|
Thyroid Nodule
|
|
0.100 |
GeneticVariation
|
BEFREE |
Using pyrosequencing and quantitative methylation-specific PCR (Q-MSP) methods, FNABs from 79 and 38 patients with thyroid nodules in training and test groups, respectively, were analyzed for BRAF(V600E) mutation and gene methylation.
|
24588959 |
2014 |
|
rs113488022
|
|
Thyroid Nodule
|
|
0.100 |
GeneticVariation
|
BEFREE |
Value of TIRADS, BSRTC and FNA-BRAF V600E mutation analysis in differentiating high-risk thyroid nodules.
|
26597052 |
2015 |
|
rs113488022
|
|
Thyroid Nodule
|
|
0.100 |
GeneticVariation
|
BEFREE |
We found TERT promoter mutations in 0.0% (0/179) of benign thyroid nodules and 7.0% (9/129) of thyroid nodules of differentiated thyroid cancer, representing a 100% diagnostic specificity and 7.0% sensitivity, with the latter rising to 38.0% (49/129) when combined with BRAF V600E testing.
|
25121551 |
2014 |
|
rs113488022
|
|
Thyroid Nodule
|
|
0.100 |
GeneticVariation
|
BEFREE |
We found that performing BRAF(V600E) mutation analysis on the fine-needle aspiration biopsy specimens was of great help to make a therapeutic decision for thyroid nodules when the fine-needle aspiration biopsy results were equivocal.
|
21239517 |
2011 |
|
rs113488022
|
|
Thyroid Nodule
|
|
0.100 |
GeneticVariation
|
BEFREE |
We recommend that patients with a thyroid nodule with any suspicious sonographic feature undergo preoperative BRAF(V600E) testing for risk stratification and to guide the initial surgical approach in PTC.
|
25337709 |
2014 |