|
rs1333040
|
|
Intracranial Aneurysm
|
T |
0.840 |
GeneticVariation
|
GWASDB |
Susceptibility loci for intracranial aneurysm in European and Japanese populations.
|
18997786 |
2008 |
|
rs7865618
|
|
Coronary heart disease
|
A |
0.820 |
GeneticVariation
|
GWASDB |
A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease.
|
21606135 |
2011 |
|
rs2891168
|
|
Coronary Artery Disease
|
|
0.820 |
GeneticVariation
|
GWASDB |
Genomewide association analysis of coronary artery disease.
|
17634449 |
2007 |
|
rs2157719
|
|
Glioma
|
|
0.820 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies five susceptibility loci for glioma.
|
19578367 |
2009 |
|
rs2157719
|
|
Glioma
|
|
0.820 |
GeneticVariation
|
GWASDB |
Chromosome 7p11.2 (EGFR) variation influences glioma risk.
|
21531791 |
2011 |
|
rs1333042
|
|
Coronary heart disease
|
|
0.820 |
GeneticVariation
|
GWASDB |
A genome-wide association study of a coronary artery disease risk variant.
|
23364394 |
2013 |
|
rs1333042
|
|
Coronary heart disease
|
|
0.820 |
GeneticVariation
|
GWASDB |
Large-scale gene-centric analysis identifies novel variants for coronary artery disease.
|
21966275 |
2011 |
|
rs1333042
|
|
Coronary heart disease
|
|
0.820 |
GeneticVariation
|
GWASDB |
A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease.
|
21606135 |
2011 |
|
rs10965235
|
|
Endometriosis
|
C |
0.820 |
GeneticVariation
|
GWASDB |
Through a genome-wide association study and a replication study using a total of 1,907 Japanese individuals with endometriosis (cases) and 5,292 controls, we identified a significant association of endometriosis with rs10965235 (P = 5.57 x 10(-12), odds ratio = 1.44), which is located in CDKN2BAS on chromosome 9p21, encoding the cyclin-dependent kinase inhibitor 2B antisense RNA.
|
20601957 |
2010 |
|
rs10757272
|
|
Intracranial Aneurysm
|
T |
0.820 |
GeneticVariation
|
GWASDB |
Additionally, we successfully replicated and validated rs10757272 on CDKN2BAS at chromosome 9p21.3 (combined P-value = 1.55 × 10(-7); odds ratio = 1.21) to be significantly associated with IA as previously reported.
|
22286173 |
2012 |
|
rs6475606
|
|
Intracranial Aneurysm
|
T |
0.810 |
GeneticVariation
|
GWASDB |
However, the metaanalysis yielded genomewide significance for SNP on chromosome 9p (CDKN2BAS; rs6475606; P=3.6×10(-8)) and provided further evidence to support the previously reported association of IA with SNP in SOX17 on chromosome 8q (rs1072737; P=8.7×10(-5)).
|
22961961 |
2012 |
|
rs564398
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
T |
0.810 |
GeneticVariation
|
GWASDB |
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
|
17463249 |
2007 |
|
rs523096
|
|
Glaucoma
|
A |
0.810 |
GeneticVariation
|
GWASDB |
The SNPs near rs523096 were recently reported to be associated with OAG associated with elevated IOP in primary open-angle glaucoma (POAG), the predominant subtype of glaucoma in Caucasian populations.
|
22792221 |
2012 |
|
rs4977756
|
|
Glaucoma, Open-Angle
|
|
0.810 |
GeneticVariation
|
GWASDB |
Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma.
|
22570617 |
2012 |
|
rs1412829
|
|
Glioma
|
|
0.810 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies five susceptibility loci for glioma.
|
19578367 |
2009 |
|
rs1412829
|
|
Glioma
|
C |
0.810 |
GeneticVariation
|
GWASDB |
Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.
|
19578366 |
2009 |
|
rs1412829
|
|
Glioma
|
|
0.810 |
GeneticVariation
|
GWASDB |
Chromosome 7p11.2 (EGFR) variation influences glioma risk.
|
21531791 |
2011 |
|
rs1333042
|
|
Coronary Artery Disease
|
|
0.810 |
GeneticVariation
|
GWASDB |
Genomewide association analysis of coronary artery disease.
|
17634449 |
2007 |
|
rs10738607
|
|
Myocardial Infarction
|
|
0.810 |
GeneticVariation
|
GWASDB |
A common variant on chromosome 9p21 affects the risk of myocardial infarction.
|
17478679 |
2007 |
|
rs1063192
|
|
Glaucoma, Open-Angle
|
T |
0.810 |
GeneticVariation
|
GWASDB |
A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma.
|
22419738 |
2012 |
|
rs1063192
|
|
Glaucoma, Open-Angle
|
|
0.810 |
GeneticVariation
|
GWASDB |
Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma.
|
22570617 |
2012 |
|
rs944801
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.800 |
GeneticVariation
|
GWASDB |
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
|
22885922 |
2012 |
|
rs944801
|
|
Glaucoma, Open-Angle
|
|
0.800 |
GeneticVariation
|
GWASDB |
Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma.
|
22570617 |
2012 |
|
rs944800
|
|
Glaucoma, Open-Angle
|
|
0.800 |
GeneticVariation
|
GWASDB |
Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma.
|
22570617 |
2012 |
|
rs944797
|
|
Coronary heart disease
|
C |
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide association study of coronary artery disease in the Japanese.
|
21971053 |
2012 |