DisGeNET - a database of gene-disease associations

Source: GWASDB

Gene: CDKN2B-AS1 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs1333046

CDKN2B-AS1

CUI:	C0027051
Disease:	Myocardial Infarction

Myocardial Infarction

0.700

GeneticVariation

GWASDB

A common variant on chromosome 9p21 affects the risk of myocardial infarction.

17478679

2007

dbSNP:

rs10965219

CDKN2B-AS1

CUI:	C1956346
Disease:	Coronary Artery Disease

Coronary Artery Disease

0.700

GeneticVariation

GWASDB

Genomewide association analysis of coronary artery disease.

17634449

2007

dbSNP:

rs10965215

CDKN2B-AS1

CUI:	C1956346
Disease:	Coronary Artery Disease

Coronary Artery Disease

0.700

GeneticVariation

GWASDB

Genomewide association analysis of coronary artery disease.

17634449

2007

dbSNP:

rs10965212

CDKN2B-AS1

CUI:	C1956346
Disease:	Coronary Artery Disease

Coronary Artery Disease

0.700

GeneticVariation

GWASDB

Genomewide association analysis of coronary artery disease.

17634449

2007

dbSNP:

rs10811650

CDKN2B-AS1

CUI:	C0027051
Disease:	Myocardial Infarction

Myocardial Infarction

0.700

GeneticVariation

GWASDB

A common variant on chromosome 9p21 affects the risk of myocardial infarction.

17478679

2007

dbSNP:

rs10757264

CDKN2B-AS1

CUI:	C1956346
Disease:	Coronary Artery Disease

Coronary Artery Disease

0.700

GeneticVariation

GWASDB

Genomewide association analysis of coronary artery disease.

17634449

2007

dbSNP:

rs10116277

CDKN2B-AS1

CUI:	C0027051
Disease:	Myocardial Infarction

Myocardial Infarction

0.700

GeneticVariation

GWASDB

A common variant on chromosome 9p21 affects the risk of myocardial infarction.

17478679

2007

dbSNP:

rs1333040

CDKN2B-AS1

CUI:	C0007766
Disease:	Intracranial Aneurysm

Intracranial Aneurysm

0.840

GeneticVariation

GWASDB

Susceptibility loci for intracranial aneurysm in European and Japanese populations.

18997786

2008

dbSNP:

rs4977756

CDKN2B-AS1

CUI:	C0017638
Disease:	Glioma

Glioma

0.900

GeneticVariation

GWASDB

We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)).

19578367

2009

dbSNP:

rs4977574

CDKN2B-AS1

CUI:	C0027051
Disease:	Myocardial Infarction

Myocardial Infarction

0.880

GeneticVariation

GWASDB

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.

19198609

2009

dbSNP:

rs2157719

CDKN2B-AS1

CUI:	C0017638
Disease:	Glioma

Glioma

0.820

GeneticVariation

GWASDB

Genome-wide association study identifies five susceptibility loci for glioma.

19578367

2009

dbSNP:

rs1412829

CDKN2B-AS1

CUI:	C0017638
Disease:	Glioma

Glioma

0.810

GeneticVariation

GWASDB

Genome-wide association study identifies five susceptibility loci for glioma.

19578367

2009

dbSNP:

rs1412829

CDKN2B-AS1

CUI:	C0017638
Disease:	Glioma

Glioma

0.810

GeneticVariation

GWASDB

Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.

19578366

2009

dbSNP:

rs1412829

CDKN2B-AS1

CUI:	C0085136
Disease:	Central Nervous System Neoplasms

Central Nervous System Neoplasms

0.800

GeneticVariation

GWASDB

Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.

19578366

2009

dbSNP:

rs1063192

CDKN2B ; CDKN2B-AS1

CUI:	C0017638
Disease:	Glioma

Glioma

0.710

GeneticVariation

GWASDB

Genome-wide association study identifies five susceptibility loci for glioma.

19578367

2009

dbSNP:

rs1333040

CDKN2B-AS1

CUI:	C0007766
Disease:	Intracranial Aneurysm

Intracranial Aneurysm

0.840

GeneticVariation

GWASDB

Genome-wide association study of intracranial aneurysm identifies three new risk loci.

20364137

2010

dbSNP:

rs10965235

CDKN2B-AS1

CUI:	C0014175
Disease:	Endometriosis

Endometriosis

0.820

GeneticVariation

GWASDB

Through a genome-wide association study and a replication study using a total of 1,907 Japanese individuals with endometriosis (cases) and 5,292 controls, we identified a significant association of endometriosis with rs10965235 (P = 5.57 x 10(-12), odds ratio = 1.44), which is located in CDKN2BAS on chromosome 9p21, encoding the cyclin-dependent kinase inhibitor 2B antisense RNA.

20601957

2010

dbSNP:

rs2383207

CDKN2B-AS1

CUI:	C0162871
Disease:	Aortic Aneurysm, Abdominal

Aortic Aneurysm, Abdominal

0.800

GeneticVariation

GWASDB

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm.

20622881

2010

dbSNP:

rs1011970

CDKN2B-AS1

CUI:	C0006142
Disease:	Malignant neoplasm of breast

Malignant neoplasm of breast

0.740

GeneticVariation

GWASDB

Genome-wide association study identifies five new breast cancer susceptibility loci.

20453838

2010

dbSNP:

rs1412829

CDKN2B-AS1

CUI:	C2931822
Disease:	Nasopharyngeal carcinoma

Nasopharyngeal carcinoma

0.720

GeneticVariation

GWASDB

A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci.

20512145

2010

dbSNP:

rs4977756

CDKN2B-AS1

CUI:	C2931822
Disease:	Nasopharyngeal carcinoma

Nasopharyngeal carcinoma

0.710

GeneticVariation

GWASDB

A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci.

20512145

2010

dbSNP:

rs2383207

CDKN2B-AS1

CUI:	C0007766
Disease:	Intracranial Aneurysm

Intracranial Aneurysm

0.700

GeneticVariation

GWASDB

Genome-wide association study of intracranial aneurysm identifies three new risk loci.

20364137

2010

dbSNP:

rs4977756

CDKN2B-AS1

CUI:	C0017638
Disease:	Glioma

Glioma

0.900

GeneticVariation

GWASDB

Chromosome 7p11.2 (EGFR) variation influences glioma risk.

21531791

2011

dbSNP:

rs1333049

CDKN2B-AS1

CUI:	C0010068
Disease:	Coronary heart disease

Coronary heart disease

0.900

GeneticVariation

GWASDB

A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease.

21606135

2011

dbSNP:

rs1333049

CDKN2B-AS1

CUI:	C0010068
Disease:	Coronary heart disease

Coronary heart disease

0.900

GeneticVariation

GWASDB

Large-scale gene-centric analysis identifies novel variants for coronary artery disease.

21966275

2011