Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.400 None 0.967 120 5 1990 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.400 None 0.911 146 4 1986 2020
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		Q9UIF7 mutY DNA glycosylase Enzyme 156 0.521 0.769 1.3E-18 0.100 None 1.000 29 3 2002 2017
Entrez Id: 1401
Gene Symbol: CRP
CRP 		P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.080 None 0.875 8 3 2000 2018
Entrez Id: 54578
Gene Symbol: UGT1A6
UGT1A6 		P19224 UDP glucuronosyltransferase family 1 member A6 115 0.560 0.654 3.0E-07 0.030 None 0.333 3 3 2005 2012
Entrez Id: 9247
Gene Symbol: GCM2
GCM2 		O75603 glial cells missing transcription factor 2 54 0.647 0.538 9.1E-04 0.030 None 1.000 3 3 2002 2004
Entrez Id: 6573
Gene Symbol: SLC19A1
SLC19A1 		P41440 solute carrier family 19 member 1 Transporter 155 0.523 0.692 6.5E-06 0.310 None 1.000 2 3 2007 2011
Entrez Id: 79068
Gene Symbol: FTO
FTO 		Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 286 0.486 0.885 8.4E-08 0.010 None 1.000 1 3 2012 2012
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1368 0.303 0.885 1.00 0.400 None 0.959 97 2 1996 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.400 None 0.944 90 2 1991 2020
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.100 None 0.981 52 2 2002 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.100 None 0.913 46 2 1994 2019
Entrez Id: 3762
Gene Symbol: KCNJ5
KCNJ5 		P48544 potassium inwardly rectifying channel subfamily J member 5 Ion channel 123 0.560 0.577 3.4E-04 0.400 None 1.000 34 2 2012 2019
Entrez Id: 9049
Gene Symbol: AIP
AIP 		O00170 aryl hydrocarbon receptor interacting protein Chaperone 216 0.517 0.769 0.36 0.400 None 1.000 15 2 2007 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.100 None 0.846 13 2 1999 2013
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		P52701 mutS homolog 6 Nucleic acid binding 296 0.462 0.731 3.7E-05 0.080 None 1.000 8 2 2006 2019
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1 		P07099 epoxide hydrolase 1 196 0.500 0.846 3.2E-09 0.050 None 0.800 5 2 2001 2007
Entrez Id: 4968
Gene Symbol: OGG1
OGG1 		O15527 8-oxoguanine DNA glycosylase 313 0.453 0.808 3.9E-12 0.050 None 0.800 5 2 2005 2011
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		P14416 dopamine receptor D2 G-protein coupled receptor 437 0.436 0.846 0.75 0.030 None 1.000 3 2 2001 2016
Entrez Id: 3973
Gene Symbol: LHCGR
LHCGR 		P22888 luteinizing hormone/choriogonadotropin receptor G-protein coupled receptor 151 0.528 0.692 5.3E-08 0.030 None 1.000 3 2 2006 2015
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1 		P23219 prostaglandin-endoperoxide synthase 1 Enzyme 318 0.460 0.885 6.2E-07 0.030 None 1.000 3 2 2001 2007
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1 		P09211 glutathione S-transferase pi 1 610 0.383 0.923 1.4E-02 0.010 None 1.000 1 2 2007 2007
Entrez Id: 3077
Gene Symbol: HFE
HFE 		Q30201 homeostatic iron regulator 415 0.436 0.846 2.6E-08 0.010 None < 0.001 1 2 2005 2005
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.010 None 1.000 1 2 2018 2018
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.100 None 0.886 35 1 1994 2018