Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1 		P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 519 0.410 0.885 1.7E-05 0.100 None 0.968 31 1 2005 2020
Entrez Id: 1401
Gene Symbol: CRP
CRP 		P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.080 None 0.875 8 0 2000 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.050 None 1.000 5 0 2001 2019
Entrez Id: 2312
Gene Symbol: FLG
FLG 		P20930 filaggrin Cellular structure 173 0.525 0.846 2.9E-04 0.100 None 1.000 4 1 2006 2006
Entrez Id: 339400
Gene Symbol: FLG-AS1
FLG-AS1 		FLG antisense RNA 1 43 0.700 0.538 0.100 None 1.000 4 1 2006 2006
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.030 None 1.000 3 2 2012 2015
Entrez Id: 3077
Gene Symbol: HFE
HFE 		Q30201 homeostatic iron regulator 415 0.436 0.846 2.6E-08 0.130 None 1.000 3 2 2007 2018
Entrez Id: 7421
Gene Symbol: VDR
VDR 		P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.020 None 1.000 2 0 2013 2018
Entrez Id: 49
Gene Symbol: ACR
ACR 		P10323 acrosin Enzyme 230 0.493 0.846 1.2E-02 0.020 None 1.000 2 0 2017 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2367 0.248 0.962 0.32 0.120 None 1.000 2 0 2004 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.020 None 0.500 2 0 2000 2006
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.020 None 1.000 2 0 1998 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.120 None 1.000 2 0 2016 2019
Entrez Id: 4314
Gene Symbol: MMP3
MMP3 		P08254 matrix metallopeptidase 3 Enzyme 473 0.408 0.885 5.7E-15 0.020 None 1.000 2 0 2011 2019
Entrez Id: 1803
Gene Symbol: DPP4
DPP4 		P27487 dipeptidyl peptidase 4 Enzyme 451 0.420 0.808 7.3E-09 0.020 None 1.000 2 0 2017 2019
Entrez Id: 7273
Gene Symbol: TTN
TTN 		Q8WZ42 titin Kinase 366 0.470 0.885 2.6E-96 0.020 None 1.000 2 0 2018 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.020 None 0.500 2 0 2007 2018
Entrez Id: 4598
Gene Symbol: MVK
MVK 		Q03426 mevalonate kinase Kinase 139 0.576 0.731 0.17 0.410 None 1.000 2 0 1999 2001
Entrez Id: 30061
Gene Symbol: SLC40A1
SLC40A1 		Q9NP59 solute carrier family 40 member 1 Transporter 101 0.570 0.731 0.99 0.120 None 1.000 2 0 2019 2019
Entrez Id: 55065
Gene Symbol: SLC52A1
SLC52A1 		Q9NWF4 solute carrier family 52 member 1 Transporter 160 0.526 0.769 3.5E-06 0.010 None 1.000 1 0 2017 2017
Entrez Id: 4982
Gene Symbol: TNFRSF11B
TNFRSF11B 		O00300 TNF receptor superfamily member 11b 443 0.422 0.808 0.16 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5027
Gene Symbol: P2RX7
P2RX7 		Q99572 purinergic receptor P2X 7 Ion channel 337 0.450 0.808 3.3E-11 0.010 None 1.000 1 0 2018 2018
Entrez Id: 54790
Gene Symbol: TET2
TET2 		Q6N021 tet methylcytosine dioxygenase 2 362 0.458 0.808 4.3E-54 0.110 None 1.000 1 0 2019 2019
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1 		P43034 platelet activating factor acetylhydrolase 1b regulatory subunit 1 219 0.504 0.769 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5133
Gene Symbol: PDCD1
PDCD1 		Q15116 programmed cell death 1 497 0.402 0.846 0.42 0.010 None 1.000 1 0 2017 2017