Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 83 0.328 0.923 6.0E-03 0.800 None 0.970 40 0 1987 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 113 0.324 0.962 1.00 1.000 None 0.967 14 3 1983 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 98 0.292 0.923 1.00 1.000 None 0.985 9 8 2001 2020
Entrez Id: 1440
Gene Symbol: CSF3
CSF3 		P09919 colony stimulating factor 3 168 0.377 0.885 0.38 0.400 None 1.000 8 0 1993 2019
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 47 0.460 0.808 1.2E-24 0.800 None 0.963 7 139 2001 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 124 0.295 0.885 0.37 0.400 None 0.970 6 0 1987 2020
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 96 0.344 0.923 0.89 0.400 None 0.971 6 0 1990 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 1.000 None 0.973 6 9 1982 2020
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		Q86YC2 partner and localizer of BRCA2 33 0.485 0.769 3.0E-19 0.800 None 0.970 6 221 2006 2020
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1 		P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 51 0.410 0.885 1.7E-05 0.400 None 0.980 5 0 1993 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 239 0.314 0.962 1.00 0.400 None 0.957 5 0 1998 2019
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 120 0.378 0.885 8.0E-02 0.600 None 0.906 4 0 1986 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 270 0.248 0.962 0.32 0.400 None 0.955 4 0 1998 2020
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		P04179 superoxide dismutase 2 Enzyme 285 0.379 0.923 0.15 0.400 None 0.896 4 0 1995 2019
Entrez Id: 7153
Gene Symbol: TOP2A
TOP2A 		P11388 DNA topoisomerase II alpha 24 0.497 0.731 0.99 0.400 None 0.974 4 0 1999 2019
Entrez Id: 7431
Gene Symbol: VIM
VIM 		P08670 vimentin 51 0.372 0.846 0.71 0.400 None 0.967 4 0 1989 2020
Entrez Id: 83990
Gene Symbol: BRIP1
BRIP1 		Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 21 0.507 0.731 6.2E-17 0.800 None 0.951 4 99 2001 2020
Entrez Id: 841
Gene Symbol: CASP8
CASP8 		Q14790 caspase 8 Enzyme 58 0.404 0.923 3.7E-06 0.600 None 0.979 4 0 2004 2019
Entrez Id: 857
Gene Symbol: CAV1
CAV1 		Q03135 caveolin 1 Enzyme modulator 58 0.388 0.885 8.3E-03 0.800 None 0.977 4 1 1999 2019
Entrez Id: 9582
Gene Symbol: APOBEC3B
APOBEC3B 		Q9UH17 apolipoprotein B mRNA editing enzyme catalytic subunit 3B Enzyme 21 0.547 0.731 5.2E-16 0.400 None 0.967 4 0 2010 2019
Entrez Id: 1312
Gene Symbol: COMT
COMT 		P21964 catechol-O-methyltransferase Enzyme 82 0.400 0.923 1.1E-06 0.400 None 0.825 3 0 1997 2019
Entrez Id: 1950
Gene Symbol: EGF
EGF 		P01133 epidermal growth factor 45 0.357 0.923 8.5E-17 0.400 None 0.980 3 0 1985 2019
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		Q92731 estrogen receptor 2 Nuclear receptor 73 0.400 0.923 4.5E-08 0.600 None 0.970 3 0 1996 2020
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2 		P21802 fibroblast growth factor receptor 2 Kinase 93 0.380 0.808 1.00 0.700 None 0.942 3 11 1991 2020
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 231 0.276 0.962 0.13 0.400 None 1.000 3 0 1991 2020