Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1495
Gene Symbol: CTNNA1
CTNNA1
P35221 catenin alpha 1 Cellular structure 82 0.584 0.538 0.97 0.300 0 0
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.300 None 1.000 1 0 1995 1995
Entrez Id: 581
Gene Symbol: BAX
BAX
Q07812 BCL2 associated X, apoptosis regulator Signaling 420 0.417 0.885 0.32 0.010 None 1.000 1 0 2002 2002
Entrez Id: 351
Gene Symbol: APP
APP
P05067 amyloid beta precursor protein Enzyme modulator 485 0.422 0.846 4.7E-02 0.010 None 1.000 1 0 2002 2002
Entrez Id: 834
Gene Symbol: CASP1
CASP1
P29466 caspase 1 Enzyme 444 0.413 0.885 3.5E-05 0.010 None 1.000 1 0 2002 2002
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
P37173 transforming growth factor beta receptor 2 Kinase 502 0.413 0.846 0.13 0.320 None 1.000 3 0 1998 2004
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.010 None 1.000 1 0 2005 2005
Entrez Id: 4582
Gene Symbol: MUC1
MUC1
P15941 mucin 1, cell surface associated 594 0.384 0.885 1.9E-02 0.010 None 1.000 1 0 2006 2006
Entrez Id: 1586
Gene Symbol: CYP17A1
CYP17A1
P05093 cytochrome P450 family 17 subfamily A member 1 326 0.462 0.769 2.6E-04 0.010 None 1.000 1 0 2007 2007
Entrez Id: 6041
Gene Symbol: RNASEL
RNASEL
Q05823 ribonuclease L Kinase 85 0.579 0.692 2.0E-10 0.010 None 1.000 1 0 2007 2007
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
O14965 aurora kinase A Kinase 245 0.475 0.731 0.87 0.010 None 1.000 1 0 2007 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.010 None 1.000 1 0 2007 2007
Entrez Id: 1312
Gene Symbol: COMT
COMT
P21964 catechol-O-methyltransferase Enzyme 622 0.400 0.923 1.1E-06 0.010 None 1.000 1 0 2007 2007
Entrez Id: 768
Gene Symbol: CA9
CA9
Q16790 carbonic anhydrase 9 226 0.483 0.731 1.3E-09 0.010 None 1.000 1 0 2007 2007
Entrez Id: 4629
Gene Symbol: MYH11
MYH11
P35749 myosin heavy chain 11 161 0.528 0.731 0.77 0.010 None 1.000 1 0 2008 2008
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 379 0.436 0.846 1.1E-17 0.010 None 1.000 1 0 2008 2008
Entrez Id: 27030
Gene Symbol: MLH3
MLH3
Q9UHC1 mutL homolog 3 Nucleic acid binding 108 0.582 0.538 4.9E-08 0.500 moderate 1.000 7 0 2003 2009
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
Q9UQ84 exonuclease 1 Enzyme 87 0.578 0.692 8.1E-13 0.310 disputed 1.000 6 0 2000 2014
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
P46527 cyclin dependent kinase inhibitor 1B 454 0.409 0.769 0.62 0.300 limited 1.000 8 0 1998 2015
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
P07099 epoxide hydrolase 1 196 0.500 0.846 3.2E-09 0.300 limited 1.000 3 0 1994 2015
Entrez Id: 64332
Gene Symbol: NFKBIZ
NFKBIZ
Q9BYH8 NFKB inhibitor zeta 30 0.674 0.577 1.00 0.300 limited 1.000 1 0 2015 2015
Entrez Id: 7518
Gene Symbol: XRCC4
XRCC4
Q13426 X-ray repair cross complementing 4 192 0.528 0.769 8.3E-07 0.300 limited 1.000 1 0 2015 2015
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 508 0.401 0.808 0.15 0.300 limited 1.000 6 0 1998 2016
Entrez Id: 4437
Gene Symbol: MSH3
MSH3
P20585 mutS homolog 3 Nucleic acid binding 245 0.474 0.769 7.4E-31 0.300 limited 1.000 6 0 1996 2016
Entrez Id: 580
Gene Symbol: BARD1
BARD1
Q99728 BRCA1 associated RING domain 1 75 0.597 0.538 1.4E-24 0.300 limited 1.000 4 0 2001 2016