Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 1.000 None 0.961 306 101 1972 2019
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 434 0.423 0.923 2.0E-30 0.100 None 1.000 13 1 2004 2013
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 0.917 12 0 2000 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.430 None 1.000 9 6 2005 2016
Entrez Id: 100144748
Gene Symbol: KLLN
KLLN
B2CW77 killin, p53 regulated DNA replication inhibitor 95 0.578 0.654 5.1E-03 0.370 None 1.000 7 2 2010 2017
Entrez Id: 7011
Gene Symbol: TEP1
TEP1
Q99973 telomerase associated protein 1 54 0.621 0.654 4.4E-49 0.060 None 1.000 6 0 1998 2002
Entrez Id: 6390
Gene Symbol: SDHB
SDHB
P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 316 0.474 0.846 2.4E-04 0.450 None 1.000 5 2 2008 2015
Entrez Id: 657
Gene Symbol: BMPR1A
BMPR1A
P36894 bone morphogenetic protein receptor type 1A Kinase 203 0.522 0.731 0.90 0.050 None 0.800 5 1 2001 2015
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.050 None 1.000 5 0 2000 2019
Entrez Id: 149233
Gene Symbol: IL23R
IL23R
Q5VWK5 interleukin 23 receptor Signaling 306 0.466 0.769 5.6E-04 0.040 None 1.000 4 2 2008 2015
Entrez Id: 130497
Gene Symbol: OSR1
OSR1
Q8TAX0 odd-skipped related transcription factor 1 Transcription factor 77 0.603 0.615 0.86 0.040 None 1.000 4 0 1998 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.040 None 1.000 4 0 1998 2014
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.040 None 1.000 4 0 1996 2010
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.030 None 1.000 3 0 2005 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.030 None 1.000 3 0 2017 2019
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
P01579 interferon gamma 1519 0.288 0.962 0.47 0.030 None 1.000 3 1 2011 2017
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1
P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 427 0.416 0.846 2.4E-02 0.030 None 1.000 3 0 1999 2011
Entrez Id: 27034
Gene Symbol: ACAD8
ACAD8
Q9UKU7 acyl-CoA dehydrogenase family member 8 Enzyme 203 0.506 0.885 5.6E-14 0.030 None 0.667 3 0 2007 2019
Entrez Id: 7052
Gene Symbol: TGM2
TGM2
P21980 transglutaminase 2 Enzyme 315 0.445 0.808 6.8E-18 0.030 None 1.000 3 0 2013 2017
Entrez Id: 1757
Gene Symbol: SARDH
SARDH
Q9UL12 sarcosine dehydrogenase Enzyme 166 0.523 0.846 5.3E-16 0.030 None 1.000 3 0 2008 2012
Entrez Id: 6652
Gene Symbol: SORD
SORD
Q00796 sorbitol dehydrogenase Enzyme 113 0.552 0.769 4.5E-08 0.030 None 1.000 3 1 2008 2012
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.030 None 0.667 3 0 1996 2016
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.330 None 1.000 3 0 2002 2013
Entrez Id: 354
Gene Symbol: KLK3
KLK3
P07288 kallikrein related peptidase 3 Enzyme 358 0.443 0.885 4.4E-06 0.030 None 1.000 3 0 2017 2019
Entrez Id: 4680
Gene Symbol: CEACAM6
CEACAM6
P40199 CEA cell adhesion molecule 6 110 0.561 0.731 1.2E-06 0.030 None 1.000 3 0 2011 2018