Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.100 None 1.000 59 0 2006 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.100 None 1.000 56 0 2006 2019
Entrez Id: 4170
Gene Symbol: MCL1
MCL1
Q07820 MCL1 apoptosis regulator, BCL2 family member Signaling 375 0.430 0.808 0.96 0.100 None 1.000 53 0 2000 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.100 None 1.000 47 1 1997 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 1.000 45 2 1989 2019
Entrez Id: 1436
Gene Symbol: CSF1R
CSF1R
P07333 colony stimulating factor 1 receptor Kinase 356 0.448 0.808 0.13 0.400 None 1.000 42 0 1988 2019
Entrez Id: 171023
Gene Symbol: ASXL1
ASXL1
Q8IXJ9 ASXL transcriptional regulator 1 296 0.482 0.808 1.3E-14 0.400 None 1.000 42 0 2000 2019
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 739 0.362 0.923 1.8E-02 0.100 None 1.000 40 4 2007 2019
Entrez Id: 930
Gene Symbol: CD19
CD19
P15391 CD19 molecule 365 0.430 0.885 0.90 0.100 None 1.000 39 0 1988 2019
Entrez Id: 2078
Gene Symbol: ERG
ERG
P11308 ETS transcription factor ERG Transcription factor 298 0.453 0.808 0.96 0.400 None 1.000 38 1 1988 2019
Entrez Id: 4211
Gene Symbol: MEIS1
MEIS1
O00470 Meis homeobox 1 Enzyme 104 0.579 0.615 1.00 0.100 None 1.000 37 0 1999 2019
Entrez Id: 1387
Gene Symbol: CREBBP
CREBBP
Q92793 CREB binding protein 438 0.428 0.808 1.00 0.600 None 1.000 33 0 1996 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.400 None 1.000 31 0 2000 2019
Entrez Id: 79870
Gene Symbol: BAALC
BAALC
Q8WXS3 BAALC binder of MAP3K1 and KLF4 47 0.631 0.385 4.4E-03 0.400 None 1.000 29 0 2003 2018
Entrez Id: 290
Gene Symbol: ANPEP
ANPEP
P15144 alanyl aminopeptidase, membrane Enzyme 280 0.462 0.769 3.7E-09 0.100 None 1.000 28 0 1988 2019
Entrez Id: 3558
Gene Symbol: IL2
IL2
P60568 interleukin 2 950 0.336 0.885 0.48 0.100 None 1.000 27 0 1990 2020
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
Q06124 protein tyrosine phosphatase non-receptor type 11 702 0.385 0.923 1.00 0.800 None 1.000 26 4 2003 2019
Entrez Id: 79971
Gene Symbol: WLS
WLS
Q5T9L3 Wnt ligand secretion mediator 166 0.513 0.731 2.0E-02 0.100 None 1.000 26 0 1994 2015
Entrez Id: 65108
Gene Symbol: MARCKSL1
MARCKSL1
P49006 MARCKS like 1 169 0.508 0.731 1.4E-02 0.100 None 1.000 24 0 1994 2007
Entrez Id: 100310785
Gene Symbol: ALL1
ALL1
Leukemia, acute lymphocytic, susceptibility to, 1 52 0.636 0.269 0.100 None 1.000 23 0 1993 2018
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.100 None 1.000 23 0 2009 2019
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
P48061 C-X-C motif chemokine ligand 12 626 0.379 0.846 0.12 0.100 None 1.000 23 1 2004 2019
Entrez Id: 1977
Gene Symbol: EIF4E
EIF4E
P06730 eukaryotic translation initiation factor 4E Nucleic acid binding 317 0.448 0.846 0.94 0.100 None 1.000 22 0 1997 2019
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
P26358 DNA methyltransferase 1 Epigenetic regulator 496 0.406 0.885 1.00 0.100 None 1.000 20 0 2001 2019
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 627 0.380 0.923 2.1E-03 0.100 None 1.000 20 0 2000 2015