Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.370 limited 0.857 7 2 2012 2018
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.900 strong 0.955 22 0 1998 2020
Entrez Id: 355
Gene Symbol: FAS
FAS
P25445 Fas cell surface death receptor 754 0.372 0.923 0.81 0.400 strong 1.000 16 0 1995 2016
Entrez Id: 4068
Gene Symbol: SH2D1A
SH2D1A
O60880 SH2 domain containing 1A 160 0.525 0.731 0.39 0.470 strong 0.857 7 0 1998 2019
Entrez Id: 3981
Gene Symbol: LIG4
LIG4
P49917 DNA ligase 4 293 0.478 0.846 4.2E-06 0.420 strong 1.000 3 0 2002 2017
Entrez Id: 5551
Gene Symbol: PRF1
PRF1
P14222 perforin 1 163 0.540 0.692 5.5E-06 0.620 strong 1.000 2 0 2008 2015
Entrez Id: 641
Gene Symbol: BLM
BLM
P54132 BLM RecQ like helicase 158 0.535 0.808 1.5E-15 0.610 strong 1.000 2 0 2002 2017
Entrez Id: 7454
Gene Symbol: WAS
WAS
P42768 WASP actin nucleation promoting factor Cellular structure 204 0.529 0.808 1.00 0.610 strong 1.000 2 0 2017 2019
Entrez Id: 81704
Gene Symbol: DOCK8
DOCK8
Q8NF50 dedicator of cytokinesis 8 Enzyme modulator 112 0.578 0.731 1.5E-11 0.300 strong 0 0
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.500 None 0.981 262 0 1987 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.400 None 0.955 156 9 1986 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.100 None 0.961 155 0 1983 2020
Entrez Id: 604
Gene Symbol: BCL6
BCL6
P41182 BCL6 transcription repressor 309 0.444 0.808 0.96 0.200 None 0.983 118 0 1993 2020
Entrez Id: 943
Gene Symbol: TNFRSF8
TNFRSF8
P28908 TNF receptor superfamily member 8 301 0.444 0.808 0.86 0.100 None 0.959 98 0 1988 2020
Entrez Id: 238
Gene Symbol: ALK
ALK
Q9UM73 ALK receptor tyrosine kinase Kinase 519 0.396 0.846 3.2E-06 0.100 None 0.976 85 1 1994 2019
Entrez Id: 931
Gene Symbol: MS4A1
MS4A1
P11836 membrane spanning 4-domains A1 Receptor 451 0.411 0.846 5.1E-05 0.200 None 1.000 77 0 1987 2020
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
P35900 keratin 20 559 0.388 0.846 9.1E-11 0.100 None 1.000 76 0 1987 2020
Entrez Id: 930
Gene Symbol: CD19
CD19
P15391 CD19 molecule 365 0.430 0.885 0.90 0.200 None 1.000 72 0 1990 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.100 None 0.915 59 0 1990 2018
Entrez Id: 9260
Gene Symbol: PDLIM7
PDLIM7
Q9NR12 PDZ and LIM domain 7 Cellular structure 241 0.474 0.808 0.71 0.100 None 1.000 55 0 1990 2019
Entrez Id: 3492
Gene Symbol: IGH
IGH
immunoglobulin heavy locus 238 0.473 0.654 0.200 None 0.958 48 0 1990 2019
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.100 None 0.956 45 0 1989 2019
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 653 0.376 0.885 1.00 0.500 None 1.000 44 3 2003 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.500 None 0.951 41 0 1995 2019
Entrez Id: 4684
Gene Symbol: NCAM1
NCAM1
P13591 neural cell adhesion molecule 1 445 0.415 0.885 1.00 0.100 None 0.951 41 0 1993 2019