Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
P37173 transforming growth factor beta receptor 2 Kinase 502 0.413 0.846 0.13 0.500 None 1.000 34 4 1994 2019
Entrez Id: 7046
Gene Symbol: TGFBR1
TGFBR1
P36897 transforming growth factor beta receptor 1 Kinase 347 0.451 0.885 0.85 0.200 None 1.000 17 1 2006 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.100 None 0.917 12 0 2003 2019
Entrez Id: 2201
Gene Symbol: FBN2
FBN2
P35556 fibrillin 2 Calcium-binding protein 211 0.505 0.808 1.00 0.200 None 1.000 11 1 1993 2020
Entrez Id: 2006
Gene Symbol: ELN
ELN
P15502 elastin 545 0.415 0.885 2.1E-14 0.100 None 1.000 11 0 1990 2019
Entrez Id: 1950
Gene Symbol: EGF
EGF
P01133 epidermal growth factor 774 0.357 0.923 8.5E-17 0.100 None 1.000 10 0 1992 2013
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
P30556 angiotensin II receptor type 1 G-protein coupled receptor 440 0.423 0.846 5.3E-04 0.080 None 0.875 8 0 2008 2019
Entrez Id: 1278
Gene Symbol: COL1A2
COL1A2
P08123 collagen type I alpha 2 chain 271 0.486 0.846 1.00 0.060 None 1.000 6 0 1985 1990
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.050 None 1.000 5 0 2009 2019
Entrez Id: 1634
Gene Symbol: DCN
DCN
P07585 decorin 297 0.457 0.808 0.31 0.040 None 1.000 4 0 1990 1993
Entrez Id: 7042
Gene Symbol: TGFB2
TGFB2
P61812 transforming growth factor beta 2 Signaling 389 0.433 0.885 1.00 0.040 None 1.000 4 0 2012 2018
Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1
P02461 collagen type III alpha 1 chain 301 0.477 0.808 1.00 0.030 None 1.000 3 0 1987 2012
Entrez Id: 4087
Gene Symbol: SMAD2
SMAD2
Q15796 SMAD family member 2 Transcription factor 289 0.456 0.808 1.00 0.030 None 1.000 3 0 2018 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.020 None 1.000 2 0 2016 2018
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.310 None 1.000 2 0 2008 2019
Entrez Id: 4035
Gene Symbol: LRP1
LRP1
Q07954 LDL receptor related protein 1 252 0.482 0.769 1.00 0.020 None 1.000 2 0 2013 2014
Entrez Id: 6876
Gene Symbol: TAGLN
TAGLN
Q01995 transgelin Cellular structure 131 0.540 0.692 8.5E-02 0.020 None 1.000 2 0 2018 2020
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
P84022 SMAD family member 3 Transcription factor 470 0.415 0.923 0.80 0.020 None 1.000 2 0 2015 2018
Entrez Id: 4513
Gene Symbol: COX2
COX2
P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.020 None 1.000 2 0 2017 2018
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.310 None 1.000 2 0 2006 2008
Entrez Id: 22915
Gene Symbol: MMRN1
MMRN1
Q13201 multimerin 1 272 0.465 0.846 2.1E-25 0.020 None 1.000 2 0 2002 2005
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.020 None 1.000 2 0 2017 2017
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 783 0.364 0.923 4.0E-15 0.310 None 1.000 2 0 2014 2017
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3
P27361 mitogen-activated protein kinase 3 Kinase 647 0.379 0.885 3.7E-02 0.020 None 1.000 2 0 2018 2019
Entrez Id: 9510
Gene Symbol: ADAMTS1
ADAMTS1
Q9UHI8 ADAM metallopeptidase with thrombospondin type 1 motif 1 Enzyme 119 0.555 0.654 0.72 0.020 None 1.000 2 0 2017 2017