Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6597
Gene Symbol: SMARCA4
SMARCA4
P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 347 0.450 0.885 1.00 0.100 None 1.000 2 4 2011 2014
Entrez Id: 5426
Gene Symbol: POLE
POLE
Q07864 DNA polymerase epsilon, catalytic subunit 151 0.526 0.731 8.0E-27 0.100 None 1.000 6 2 1996 2015
Entrez Id: 6392
Gene Symbol: SDHD
SDHD
O14521 succinate dehydrogenase complex subunit D Transporter 348 0.472 0.885 0.34 0.100 None 1.000 72 31 1998 2016
Entrez Id: 641
Gene Symbol: BLM
BLM
P54132 BLM RecQ like helicase 158 0.535 0.808 1.5E-15 0.100 None 1.000 26 10 1995 2016
Entrez Id: 4286
Gene Symbol: MITF
MITF
O75030 melanocyte inducing transcription factor 244 0.499 0.808 0.98 0.100 None 1.000 22 1 1987 2016
Entrez Id: 23405
Gene Symbol: DICER1
DICER1
Q9UPY3 dicer 1, ribonuclease III Enzyme 302 0.446 0.846 1.00 0.120 None 1.000 13 90 2009 2016
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
P22897 mannose receptor C-type 1 431 0.413 0.846 0.94 0.080 None 1.000 8 0 1999 2016
Entrez Id: 55654
Gene Symbol: TMEM127
TMEM127
O75204 transmembrane protein 127 72 0.638 0.615 1.3E-02 0.100 None 1.000 4 6 2010 2016
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
Q01196 RUNX family transcription factor 1 Transcription factor 412 0.425 0.808 0.65 0.010 None 1.000 1 0 2016 2016
Entrez Id: 4437
Gene Symbol: MSH3
MSH3
P20585 mutS homolog 3 Nucleic acid binding 245 0.474 0.769 7.4E-31 0.010 None 1.000 1 0 2016 2016
Entrez Id: 80204
Gene Symbol: FBXO11
FBXO11
Q86XK2 F-box protein 11 Enzyme 93 0.604 0.692 1.00 0.100 None 1.000 187 321 1994 2017
Entrez Id: 7428
Gene Symbol: VHL
VHL
P40337 von Hippel-Lindau tumor suppressor Enzyme 372 0.443 0.846 8.0E-02 0.180 None 1.000 172 59 1994 2017
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.110 None 1.000 160 257 1991 2017
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.110 None 1.000 135 49 1994 2017
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Q9UIF7 mutY DNA glycosylase Enzyme 156 0.521 0.769 1.3E-18 0.100 None 1.000 123 83 2001 2017
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Q86YC2 partner and localizer of BRCA2 260 0.485 0.769 3.0E-19 0.100 None 1.000 110 293 2007 2017
Entrez Id: 83990
Gene Symbol: BRIP1
BRIP1
Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 194 0.507 0.731 6.2E-17 0.100 None 1.000 56 145 2004 2017
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
O43502 RAD51 paralog C 162 0.533 0.692 6.2E-14 0.100 None 1.000 50 65 2002 2017
Entrez Id: 4683
Gene Symbol: NBN
NBN
O60934 nibrin Nucleic acid binding 291 0.467 0.808 2.2E-16 0.100 None 1.000 36 92 1998 2017
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.100 None 1.000 35 35 1998 2017
Entrez Id: 7249
Gene Symbol: TSC2
TSC2
P49815 TSC complex subunit 2 Enzyme modulator 410 0.439 0.808 1.00 0.110 None 1.000 31 29 1994 2017
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Q92878 RAD50 double strand break repair protein 110 0.556 0.808 3.4E-27 0.100 None 1.000 31 164 1999 2017
Entrez Id: 580
Gene Symbol: BARD1
BARD1
Q99728 BRCA1 associated RING domain 1 75 0.597 0.538 1.4E-24 0.100 None 1.000 28 105 2003 2017
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
Q92826 homeobox B13 90 0.573 0.462 3.7E-08 0.100 None 1.000 26 1 1996 2017
Entrez Id: 2176
Gene Symbol: FANCC
FANCC
Q00597 FA complementation group C 218 0.507 0.808 2.8E-13 0.100 None 1.000 23 6 1993 2017