Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 Signaling 679 0.380 0.846 0.46 0.010 None < 0.001 1 0 2019 2019
Entrez Id: 2222
Gene Symbol: FDFT1
FDFT1
P37268 farnesyl-diphosphate farnesyltransferase 1 62 0.621 0.615 4.1E-15 0.010 None < 0.001 1 0 2009 2009
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
P35372 opioid receptor mu 1 G-protein coupled receptor 370 0.457 0.808 7.9E-11 0.010 None < 0.001 1 0 2018 2018
Entrez Id: 26291
Gene Symbol: FGF21
FGF21
Q9NSA1 fibroblast growth factor 21 Signaling 236 0.485 0.769 2.9E-02 0.010 None < 0.001 1 0 2019 2019
Entrez Id: 6517
Gene Symbol: SLC2A4
SLC2A4
P14672 solute carrier family 2 member 4 Transporter 158 0.528 0.769 4.7E-05 0.010 None < 0.001 1 0 2019 2019
Entrez Id: 6899
Gene Symbol: TBX1
TBX1
O43435 T-box transcription factor 1 Transcription factor 417 0.433 0.808 0.84 0.010 None < 0.001 1 0 2019 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.020 None 0.500 2 0 2007 2015
Entrez Id: 7351
Gene Symbol: UCP2
UCP2
P55851 uncoupling protein 2 Transporter 235 0.493 0.808 1.5E-10 0.020 None 0.500 2 1 2003 2012
Entrez Id: 155
Gene Symbol: ADRB3
ADRB3
P13945 adrenoceptor beta 3 G-protein coupled receptor 142 0.533 0.731 2.5E-07 0.050 None 0.600 5 1 1995 2018
Entrez Id: 7350
Gene Symbol: UCP1
UCP1
P25874 uncoupling protein 1 Transporter 124 0.545 0.769 1.7E-11 0.030 None 0.667 3 0 2009 2019
Entrez Id: 364
Gene Symbol: AQP7
AQP7
O14520 aquaporin 7 Ion channel 34 0.670 0.462 4.1E-16 0.040 None 0.750 4 0 2007 2019
Entrez Id: 2166
Gene Symbol: FAAH
FAAH
O00519 fatty acid amide hydrolase 177 0.545 0.692 4.4E-11 0.040 None 0.750 4 1 2008 2015
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
P48357 leptin receptor Signaling 416 0.433 0.808 0.99 0.400 None 0.944 18 2 1997 2020
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.400 None 0.969 32 0 1997 2020
Entrez Id: 4160
Gene Symbol: MC4R
MC4R
P32245 melanocortin 4 receptor G-protein coupled receptor 149 0.535 0.692 9.2E-04 0.400 None 0.977 43 6 1999 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 679 0.376 0.885 4.6E-09 0.100 None 1.000 14 0 2003 2019
Entrez Id: 79068
Gene Symbol: FTO
FTO
Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 286 0.486 0.885 8.4E-08 0.100 None 1.000 12 3 2007 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.080 None 1.000 8 0 2009 2019
Entrez Id: 5443
Gene Symbol: POMC
POMC
P01189 proopiomelanocortin 873 0.356 0.846 1.2E-04 0.080 None 1.000 8 1 1999 2018
Entrez Id: 6492
Gene Symbol: SIM1
SIM1
P81133 SIM bHLH transcription factor 1 Transcription factor 84 0.626 0.654 1.00 0.070 None 1.000 7 1 2000 2017
Entrez Id: 5122
Gene Symbol: PCSK1
PCSK1
P29120 proprotein convertase subtilisin/kexin type 1 Enzyme 140 0.548 0.615 2.7E-09 0.060 None 1.000 6 1 2002 2018
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.150 None 1.000 5 4 2009 2012
Entrez Id: 2572
Gene Symbol: GAD2
GAD2
Q05329 glutamate decarboxylase 2 Enzyme 173 0.529 0.731 0.75 0.050 None 1.000 5 0 2003 2006
Entrez Id: 627
Gene Symbol: BDNF
BDNF
P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.330 None 1.000 4 2 2011 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.040 None 1.000 4 0 2012 2014