Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 1.000 strong 0.961 648 189 1989 2020
Entrez Id: 7276
Gene Symbol: TTR
TTR
P02766 transthyretin Transporter 461 0.423 0.885 0.52 0.400 strong 0.980 151 13 1983 2019
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Q9UIF7 mutY DNA glycosylase Enzyme 156 0.521 0.769 1.3E-18 0.600 strong 0.927 82 4 2003 2020
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.100 None 1.000 11 3 2002 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.100 None 0.949 39 2 1986 2020
Entrez Id: 8312
Gene Symbol: AXIN1
AXIN1
O15169 axin 1 118 0.559 0.577 0.41 0.100 None 1.000 15 2 2002 2019
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
P43246 mutS homolog 2 Nucleic acid binding 490 0.406 0.808 0.90 0.100 None 1.000 15 2 1993 2018
Entrez Id: 948
Gene Symbol: CD36
CD36
P16671 CD36 molecule Receptor 351 0.446 0.846 1.1E-60 0.010 None 1.000 1 2 2018 2018
Entrez Id: 4163
Gene Symbol: MCC
MCC
P23508 MCC regulator of WNT signaling pathway 110 0.568 0.731 4.7E-16 0.400 None 1.000 18 1 1991 2018
Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
Q9Y2T1 axin 2 169 0.507 0.692 0.57 0.100 None 0.769 13 1 1999 2019
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.060 None 1.000 6 1 1995 2019
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
P52701 mutS homolog 6 Nucleic acid binding 296 0.462 0.731 3.7E-05 0.060 None 0.833 6 1 2004 2018
Entrez Id: 4913
Gene Symbol: NTHL1
NTHL1
P78549 nth like DNA glycosylase 1 Enzyme 57 0.623 0.615 5.7E-10 0.360 None 1.000 6 1 2015 2019
Entrez Id: 2328
Gene Symbol: FMO3
FMO3
P31513 flavin containing dimethylaniline monoxygenase 3 Enzyme 51 0.638 0.500 6.5E-16 0.330 None 1.000 3 1 2004 2007
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.020 None 1.000 2 1 2004 2013
Entrez Id: 2934
Gene Symbol: GSN
GSN
P06396 gelsolin Cellular structure 262 0.475 0.885 3.9E-11 0.020 None 1.000 2 1 1993 1996
Entrez Id: 100133941
Gene Symbol: CD24
CD24
P25063 CD24 molecule 244 0.472 0.769 0.010 None 1.000 1 1 2015 2015
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 336 0.449 0.885 9.8E-24 0.010 None 1.000 1 1 2011 2011
Entrez Id: 1856
Gene Symbol: DVL2
DVL2
O14641 dishevelled segment polarity protein 2 Signaling 58 0.621 0.577 1.4E-05 0.010 None 1.000 1 1 2019 2019
Entrez Id: 6311
Gene Symbol: ATXN2
ATXN2
Q99700 ataxin 2 Nucleic acid binding 341 0.482 0.808 0.85 0.010 None 1.000 1 1 2019 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.100 None 0.981 372 0 1995 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 0.912 68 0 1992 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.400 None 1.000 34 0 1997 2019
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.100 None 0.955 22 0 1993 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.100 None 1.000 21 0 1996 2017