Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.010 None 1.000 1 0 2012 2012
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.010 None 1.000 1 0 2015 2015
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.010 None 1.000 1 1 2011 2011
Entrez Id: 7421
Gene Symbol: VDR
VDR
P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.100 None 0 0
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.010 None 1.000 1 0 1995 1995
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.100 None 0 0
Entrez Id: 8626
Gene Symbol: TP63
TP63
Q9H3D4 tumor protein p63 Transcription factor 816 0.362 0.769 1.00 0.300 None 1.000 1 0 1999 1999
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.010 None 1.000 1 0 2015 2015
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
Q16539 mitogen-activated protein kinase 14 Kinase 626 0.379 0.923 0.37 0.010 None 1.000 1 0 2012 2012
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 Enzyme 668 0.379 0.923 0.15 0.300 None 1.000 1 0 2014 2014
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
P21802 fibroblast growth factor receptor 2 Kinase 731 0.380 0.808 1.00 0.310 None 1.000 2 0 2000 2012
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
P02545 lamin A/C 824 0.384 0.885 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5340
Gene Symbol: PLG
PLG
P00747 plasminogen Enzyme 586 0.389 0.923 1.0E-02 0.110 None 1.000 1 0 1995 1995
Entrez Id: 7965
Gene Symbol: AIMP2
AIMP2
Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 555 0.393 0.923 8.0E-03 0.010 None 1.000 1 0 2012 2012
Entrez Id: 1398
Gene Symbol: CRK
CRK
P46108 CRK proto-oncogene, adaptor protein 544 0.394 0.923 0.96 0.010 None 1.000 1 0 2012 2012
Entrez Id: 9402
Gene Symbol: GRAP2
GRAP2
O75791 GRB2 related adaptor protein 2 538 0.394 0.923 1.5E-04 0.010 None 1.000 1 0 2012 2012
Entrez Id: 10598
Gene Symbol: AHSA1
AHSA1
O95433 activator of HSP90 ATPase activity 1 526 0.396 0.923 1.00 0.010 None 1.000 1 0 2012 2012
Entrez Id: 26073
Gene Symbol: POLDIP2
POLDIP2
Q9Y2S7 DNA polymerase delta interacting protein 2 530 0.396 0.923 0.41 0.010 None 1.000 1 0 2012 2012
Entrez Id: 25897
Gene Symbol: RNF19A
RNF19A
Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 523 0.397 0.923 2.5E-02 0.010 None 1.000 1 0 2012 2012
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.010 None 1.000 1 0 2012 2012
Entrez Id: 4204
Gene Symbol: MECP2
MECP2
P51608 methyl-CpG binding protein 2 Epigenetic regulator 664 0.414 0.846 0.89 0.100 None 0 1
Entrez Id: 5159
Gene Symbol: PDGFRB
PDGFRB
P09619 platelet derived growth factor receptor beta Kinase 492 0.416 0.846 0.90 0.100 None 0 0
Entrez Id: 2200
Gene Symbol: FBN1
FBN1
P35555 fibrillin 1 Calcium-binding protein 552 0.417 0.846 1.00 0.100 None 0 2
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 499 0.420 0.846 7.1E-20 0.310 None 1.000 2 0 2007 2013