Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 9 0.281 0.923 5.9E-03 0.200 None 0.933 1 1 2001 2020
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 10 0.320 0.923 1.00 0.190 None 1.000 1 1 2010 2018
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 9 0.321 0.962 4.6E-09 0.200 None 0.786 1 1 2005 2019
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 7 0.364 0.923 4.0E-15 0.110 None 1.000 3 4 2003 2019
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 9 0.369 0.885 1.00 0.110 None 1.000 1 1 2015 2016
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
P04439 major histocompatibility complex, class I, A 48 0.370 0.846 1.3E-03 0.160 None 1.000 1 1 1985 2015
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
P01889 major histocompatibility complex, class I, B 94 0.379 0.885 3.9E-05 0.500 None 0.955 1 2 1980 2020
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
P01589 interleukin 2 receptor subunit alpha Receptor 39 0.389 0.885 5.5E-02 0.130 None 1.000 2 4 2014 2019
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
P19838 nuclear factor kappa B subunit 1 Transcription factor 18 0.396 0.923 1.00 0.140 None 1.000 1 1 2005 2018
Entrez Id: 958
Gene Symbol: CD40
CD40
P25942 CD40 molecule 9 0.396 0.846 0.85 0.110 None 1.000 1 1 2016 2018
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
P19438 TNF receptor superfamily member 1A 13 0.409 0.923 0.99 0.200 None 1.000 2 1 2005 2019
Entrez Id: 196
Gene Symbol: AHR
AHR
P35869 aryl hydrocarbon receptor Transcription factor 19 0.410 0.923 1.00 0.110 None 1.000 1 1 2016 2019
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
P84022 SMAD family member 3 Transcription factor 53 0.415 0.923 0.80 0.100 None 1.000 2 3 2015 2016
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 9 0.423 0.923 2.0E-30 0.160 None 0.714 1 3 2002 2018
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
P00749 plasminogen activator, urokinase Enzyme 7 0.425 0.923 2.3E-06 0.100 None 1.000 1 1 2016 2016
Entrez Id: 6794
Gene Symbol: STK11
STK11
Q15831 serine/threonine kinase 11 Kinase 5 0.435 0.808 0.99 0.100 None 1.000 1 1 2016 2016
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 34 0.438 0.846 3.5E-21 0.150 None 1.000 1 1 2014 2017
Entrez Id: 4210
Gene Symbol: MEFV
MEFV
O15553 MEFV innate immuity regulator, pyrin 1 0.440 0.885 1.0E-14 0.200 None 1.000 1 1 2008 2019
Entrez Id: 2113
Gene Symbol: ETS1
ETS1
P14921 ETS proto-oncogene 1, transcription factor Transcription factor 24 0.444 0.731 0.78 0.110 None 1.000 1 2 2014 2016
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
Q9Y6K1 DNA methyltransferase 3 alpha 12 0.445 0.846 7.4E-39 0.100 None 1.000 1 1 2016 2016
Entrez Id: 5579
Gene Symbol: PRKCB
PRKCB
P05771 protein kinase C beta Kinase 10 0.453 0.885 1.00 0.100 None 1.000 1 1 2016 2016
Entrez Id: 246778
Gene Symbol: IL27
IL27
Q8NEV9 interleukin 27 10 0.457 0.808 0.78 0.100 None 1.000 1 1 2016 2016
Entrez Id: 9474
Gene Symbol: ATG5
ATG5
Q9H1Y0 autophagy related 5 Transporter 16 0.462 0.885 0.98 0.120 None 1.000 1 1 2014 2018
Entrez Id: 4485
Gene Symbol: MST1
MST1
P26927 macrophage stimulating 1 Enzyme 7 0.465 0.885 4.8E-19 0.100 None 1.000 1 1 2016 2016
Entrez Id: 149233
Gene Symbol: IL23R
IL23R
Q5VWK5 interleukin 23 receptor Signaling 22 0.466 0.769 5.6E-04 0.500 None 0.964 5 6 2007 2019