Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1268
Gene Symbol: CNR1
CNR1
P21554 cannabinoid receptor 1 G-protein coupled receptor 393 0.446 0.808 0.51 0.090 None 0.889 9 5 2004 2020
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
P14416 dopamine receptor D2 G-protein coupled receptor 437 0.436 0.846 0.75 0.100 None 1.000 27 4 1994 2020
Entrez Id: 4986
Gene Symbol: OPRK1
OPRK1
P41145 opioid receptor kappa 1 G-protein coupled receptor 156 0.555 0.615 4.1E-05 0.100 None 1.000 11 4 2012 2019
Entrez Id: 1312
Gene Symbol: COMT
COMT
P21964 catechol-O-methyltransferase Enzyme 622 0.400 0.923 1.1E-06 0.050 None 1.000 5 3 2004 2018
Entrez Id: 1621
Gene Symbol: DBH
DBH
P09172 dopamine beta-hydroxylase 202 0.511 0.846 3.3E-10 0.010 None 1.000 1 3 2016 2016
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
P35372 opioid receptor mu 1 G-protein coupled receptor 370 0.457 0.808 7.9E-11 0.100 None 1.000 23 2 1999 2020
Entrez Id: 627
Gene Symbol: BDNF
BDNF
P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.100 None 1.000 17 2 2005 2020
Entrez Id: 255239
Gene Symbol: ANKK1
ANKK1
Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 71 0.604 0.462 7.4E-12 0.100 None 0.900 10 2 2004 2017
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.040 None 1.000 4 2 2003 2019
Entrez Id: 590
Gene Symbol: BCHE
BCHE
P06276 butyrylcholinesterase 392 0.447 0.923 1.1E-13 0.030 None 1.000 3 2 2017 2019
Entrez Id: 43
Gene Symbol: ACHE
ACHE
P22303 acetylcholinesterase (Cartwright blood group) Enzyme 418 0.445 0.885 1.00 0.020 None 1.000 2 2 2017 2019
Entrez Id: 2166
Gene Symbol: FAAH
FAAH
O00519 fatty acid amide hydrolase 177 0.545 0.692 4.4E-11 0.080 None 1.000 8 1 2004 2020
Entrez Id: 1137
Gene Symbol: CHRNA4
CHRNA4
P43681 cholinergic receptor nicotinic alpha 4 subunit Ion channel 248 0.492 0.808 8.5E-05 0.040 None 1.000 4 1 1998 2020
Entrez Id: 1387
Gene Symbol: CREBBP
CREBBP
Q92793 CREB binding protein 438 0.428 0.808 1.00 0.020 None 1.000 2 1 2011 2016
Entrez Id: 4985
Gene Symbol: OPRD1
OPRD1
P41143 opioid receptor delta 1 G-protein coupled receptor 92 0.604 0.731 3.3E-03 0.020 None 1.000 2 1 2006 2013
Entrez Id: 2555
Gene Symbol: GABRA2
GABRA2
P47869 gamma-aminobutyric acid type A receptor subunit alpha2 Ion channel 60 0.641 0.346 1.00 0.020 None 1.000 2 1 2006 2010
Entrez Id: 6857
Gene Symbol: SYT1
SYT1
P21579 synaptotagmin 1 Transporter 460 0.412 0.846 0.60 0.010 None 1.000 1 1 2019 2019
Entrez Id: 4306
Gene Symbol: NR3C2
NR3C2
P08235 nuclear receptor subfamily 3 group C member 2 Nuclear receptor 287 0.469 0.846 0.84 0.010 None 1.000 1 1 2014 2014
Entrez Id: 7054
Gene Symbol: TH
TH
P07101 tyrosine hydroxylase 321 0.462 0.885 1.7E-06 0.010 None 1.000 1 1 2004 2004
Entrez Id: 1393
Gene Symbol: CRHBP
CRHBP
P24387 corticotropin releasing hormone binding protein Signaling 48 0.659 0.500 0.21 0.010 None 1.000 1 1 2008 2008
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.010 None 1.000 1 1 2009 2009
Entrez Id: 8440
Gene Symbol: NCK2
NCK2
O43639 NCK adaptor protein 2 25 0.743 0.500 0.46 0.100 None 1.000 1 1 2013 2013
Entrez Id: 23114
Gene Symbol: NFASC
NFASC
O94856 neurofascin 62 0.682 0.423 1.00 0.100 None 1.000 1 1 2013 2013
Entrez Id: 284
Gene Symbol: ANGPT1
ANGPT1
Q15389 angiopoietin 1 Signaling 340 0.446 0.808 0.95 0.010 None 1.000 1 1 2019 2019
Entrez Id: 1392
Gene Symbol: CRH
CRH
P06850 corticotropin releasing hormone Signaling 402 0.439 0.808 0.72 0.100 None 1.000 14 0 2013 2019