Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2775
Gene Symbol: GNAO1
GNAO1
P09471 G protein subunit alpha o1 Enzyme modulator 188 0.523 0.808 0.99 0.300 None 1.000 1 0 2002 2002
Entrez Id: 135
Gene Symbol: ADORA2A
ADORA2A
P29274 adenosine A2a receptor G-protein coupled receptor 213 0.526 0.769 0.60 0.300 None 1.000 3 0 2004 2006
Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7
P36544 Q494W8 cholinergic receptor nicotinic alpha 7 subunit Ion channel 172 0.532 0.654 4.2E-04 0.300 None 1.000 1 0 2008 2008
Entrez Id: 4086
Gene Symbol: SMAD1
SMAD1
Q15797 SMAD family member 1 Transcription factor 138 0.533 0.731 0.99 0.300 None 1.000 1 0 2018 2018
Entrez Id: 2166
Gene Symbol: FAAH
FAAH
O00519 fatty acid amide hydrolase 177 0.545 0.692 4.4E-11 0.300 None 1.000 2 0 2008 2009
Entrez Id: 4986
Gene Symbol: OPRK1
OPRK1
P41145 opioid receptor kappa 1 G-protein coupled receptor 156 0.555 0.615 4.1E-05 0.300 None 1.000 2 0 1998 2010
Entrez Id: 3358
Gene Symbol: HTR2C
HTR2C
P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 140 0.555 0.692 3.7E-02 0.300 None 1.000 1 0 2006 2006
Entrez Id: 5187
Gene Symbol: PER1
PER1
O15534 period circadian regulator 1 Transcription factor 111 0.556 0.731 2.9E-04 0.300 None 1.000 1 0 2010 2010
Entrez Id: 8863
Gene Symbol: PER3
PER3
P56645 period circadian regulator 3 Transcription factor 122 0.559 0.731 1.4E-17 0.300 None 1.000 1 0 2010 2010
Entrez Id: 2890
Gene Symbol: GRIA1
GRIA1
P42261 glutamate ionotropic receptor AMPA type subunit 1 Ion channel 126 0.570 0.577 1.00 0.300 None 1.000 2 0 2001 2003
Entrez Id: 887
Gene Symbol: CCKBR
CCKBR
P32239 cholecystokinin B receptor G-protein coupled receptor 105 0.573 0.615 2.1E-06 0.300 None 1.000 2 0 1998 2002
Entrez Id: 2891
Gene Symbol: GRIA2
GRIA2
P42262 glutamate ionotropic receptor AMPA type subunit 2 Ion channel 110 0.573 0.692 1.00 0.300 None 1.000 1 0 2003 2003
Entrez Id: 134
Gene Symbol: ADORA1
ADORA1
P30542 adenosine A1 receptor G-protein coupled receptor 121 0.578 0.692 1.5E-02 0.300 None 1.000 1 0 2005 2005
Entrez Id: 6529
Gene Symbol: SLC6A1
SLC6A1
P30531 solute carrier family 6 member 1 Transporter 106 0.592 0.538 1.00 0.300 None 1.000 1 0 2003 2003
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5
P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 110 0.593 0.577 2.1E-06 0.300 None 1.000 1 0 2008 2008
Entrez Id: 57154
Gene Symbol: SMURF1
SMURF1
Q9HCE7 SMAD specific E3 ubiquitin protein ligase 1 Enzyme 70 0.595 0.615 0.61 0.300 None 1.000 1 0 2018 2018
Entrez Id: 5368
Gene Symbol: PNOC
PNOC
Q13519 prepronociceptin Signaling 103 0.603 0.577 1.5E-02 0.300 None 1.000 1 0 2000 2000
Entrez Id: 4985
Gene Symbol: OPRD1
OPRD1
P41143 opioid receptor delta 1 G-protein coupled receptor 92 0.604 0.731 3.3E-03 0.300 None 1.000 1 0 1985 1985
Entrez Id: 4887
Gene Symbol: NPY2R
NPY2R
P49146 neuropeptide Y receptor Y2 G-protein coupled receptor 68 0.612 0.577 3.6E-02 0.300 None 1.000 1 0 2008 2008
Entrez Id: 1141
Gene Symbol: CHRNB2
CHRNB2
P17787 cholinergic receptor nicotinic beta 2 subunit Ion channel 96 0.617 0.308 7.3E-04 0.300 None 1.000 1 0 2008 2008
Entrez Id: 4885
Gene Symbol: NPTX2
NPTX2
P47972 neuronal pentraxin 2 67 0.617 0.615 3.1E-02 0.300 None 1.000 1 0 2009 2009
Entrez Id: 3061
Gene Symbol: HCRTR1
HCRTR1
O43613 hypocretin receptor 1 G-protein coupled receptor 71 0.623 0.654 1.7E-04 0.300 None 1.000 1 0 2010 2010
Entrez Id: 4987
Gene Symbol: OPRL1
OPRL1
P41146 opioid related nociceptin receptor 1 G-protein coupled receptor 76 0.628 0.462 0.48 0.300 None 1.000 1 0 2000 2000
Entrez Id: 4090
Gene Symbol: SMAD5
SMAD5
Q99717 SMAD family member 5 Transcription factor 55 0.633 0.615 1.00 0.300 None 1.000 1 0 2018 2018
Entrez Id: 1143
Gene Symbol: CHRNB4
CHRNB4
P30926 cholinergic receptor nicotinic beta 4 subunit Ion channel 75 0.644 0.423 0.14 0.300 None 1.000 1 0 2004 2004