Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7173
Gene Symbol: TPO
TPO
P07202 thyroid peroxidase Enzyme 306 0.455 0.846 1.8E-21 0.010 None 1.000 1 0 2018 2018
Entrez Id: 4312
Gene Symbol: MMP1
MMP1
P03956 matrix metallopeptidase 1 Enzyme 589 0.385 0.885 7.7E-18 0.010 None 1.000 1 0 2008 2008
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.010 None 1.000 1 0 2010 2010
Entrez Id: 1950
Gene Symbol: EGF
EGF
P01133 epidermal growth factor 774 0.357 0.923 8.5E-17 0.020 None 1.000 2 0 2014 2016
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
P21860 erb-b2 receptor tyrosine kinase 3 Kinase 318 0.448 0.808 1.7E-15 0.010 None 1.000 1 0 2005 2005
Entrez Id: 10855
Gene Symbol: HPSE
HPSE
Q9Y251 heparanase Enzyme 393 0.425 0.808 2.3E-14 0.010 None 1.000 1 0 2009 2009
Entrez Id: 57650
Gene Symbol: CIP2A
CIP2A
Q8TCG1 cellular inhibitor of PP2A 141 0.524 0.808 1.4E-13 0.010 None 1.000 1 0 2012 2012
Entrez Id: 4608
Gene Symbol: MYBPH
MYBPH
Q13203 myosin binding protein H 33 0.678 0.577 2.3E-13 0.010 None 1.000 1 0 2009 2009
Entrez Id: 2314
Gene Symbol: FLII
FLII
Q13045 FLII actin remodeling protein 198 0.520 0.808 5.5E-12 0.010 None 1.000 1 0 2019 2019
Entrez Id: 51129
Gene Symbol: ANGPTL4
ANGPTL4
Q9BY76 angiopoietin like 4 Signaling 198 0.498 0.731 2.3E-11 0.010 None 1.000 1 0 2010 2010
Entrez Id: 5052
Gene Symbol: PRDX1
PRDX1
Q06830 peroxiredoxin 1 Enzyme 237 0.485 0.846 7.7E-10 0.010 None 1.000 1 0 2005 2005
Entrez Id: 768
Gene Symbol: CA9
CA9
Q16790 carbonic anhydrase 9 226 0.483 0.731 1.3E-09 0.020 None 1.000 2 0 2010 2015
Entrez Id: 11197
Gene Symbol: WIF1
WIF1
Q9Y5W5 WNT inhibitory factor 1 Calcium-binding protein 171 0.507 0.731 1.3E-09 0.010 None 1.000 1 0 2011 2011
Entrez Id: 84282
Gene Symbol: RNF135
RNF135
Q8IUD6 ring finger protein 135 41 0.686 0.500 2.2E-09 0.010 None 1.000 1 0 2016 2016
Entrez Id: 799
Gene Symbol: CALCR
CALCR
P30988 calcitonin receptor G-protein coupled receptor 282 0.464 0.846 3.1E-09 0.010 None 1.000 1 0 2017 2017
Entrez Id: 150353
Gene Symbol: DNAJB7
DNAJB7
Q7Z6W7 DnaJ heat shock protein family (Hsp40) member B7 26 0.716 0.269 8.6E-09 0.010 None 1.000 1 0 2015 2015
Entrez Id: 1111
Gene Symbol: CHEK1
CHEK1
O14757 checkpoint kinase 1 Kinase 195 0.492 0.808 3.1E-08 0.010 None 1.000 1 0 2020 2020
Entrez Id: 3371
Gene Symbol: TNC
TNC
P24821 tenascin C 369 0.433 0.846 1.3E-07 0.010 None 1.000 1 0 2010 2010
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM
P16422 epithelial cell adhesion molecule 328 0.451 0.885 1.3E-07 0.010 None 1.000 1 0 2007 2007
Entrez Id: 64946
Gene Symbol: CENPH
CENPH
Q9H3R5 centromere protein H 26 0.705 0.308 1.5E-07 0.010 None 1.000 1 0 2009 2009
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
P04792 heat shock protein family B (small) member 1 395 0.436 0.808 2.8E-07 0.300 None 1.000 1 0 2010 2010
Entrez Id: 5617
Gene Symbol: PRL
PRL
P01236 prolactin Signaling 506 0.406 0.885 2.9E-07 0.010 None 1.000 1 0 2000 2000
Entrez Id: 27250
Gene Symbol: PDCD4
PDCD4
Q53EL6 programmed cell death 4 Nucleic acid binding 198 0.494 0.769 3.4E-07 0.020 None 1.000 2 0 2014 2019
Entrez Id: 5071
Gene Symbol: PRKN
PRKN
O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 409 0.431 0.846 6.9E-07 0.020 None 1.000 2 0 2016 2016
Entrez Id: 6821
Gene Symbol: SUOX
SUOX
P51687 sulfite oxidase 67 0.638 0.615 9.4E-07 0.010 None 1.000 1 0 2018 2018