Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6
Q9NP58 ATP binding cassette subfamily B member 6 (Langereis blood group) Transporter 400 0.431 0.885 8.6E-19 0.100 None 1.000 18 0 1989 2013
Entrez Id: 7001
Gene Symbol: PRDX2
PRDX2
P32119 peroxiredoxin 2 Enzyme 243 0.474 0.885 8.7E-02 0.100 None 1.000 18 0 1989 2013
Entrez Id: 722
Gene Symbol: C4BPA
C4BPA
P04003 complement component 4 binding protein alpha 107 0.556 0.846 0.46 0.100 None 1.000 18 0 1989 2013
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
P10636 microtubule associated protein tau 469 0.446 0.923 6.0E-03 0.060 None 0.833 6 0 2001 2017
Entrez Id: 2688
Gene Symbol: GH1
GH1
P01241 growth hormone 1 Signaling 686 0.373 0.923 3.0E-02 0.060 None 0.833 6 0 1999 2018
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.050 None 0.800 5 0 1995 2015
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
P04141 colony stimulating factor 2 Signaling 1028 0.330 0.962 0.83 0.050 None 0.800 5 0 2017 2019
Entrez Id: 5071
Gene Symbol: PRKN
PRKN
O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 409 0.431 0.846 6.9E-07 0.050 None 0.800 5 0 2009 2017
Entrez Id: 351
Gene Symbol: APP
APP
P05067 amyloid beta precursor protein Enzyme modulator 485 0.422 0.846 4.7E-02 0.050 None 0.800 5 0 2000 2019
Entrez Id: 158506
Gene Symbol: CBLL2
CBLL2
Q8N7E2 Cbl proto-oncogene like 2 Enzyme 235 0.476 0.808 0.040 None 1.000 4 0 2009 2017
Entrez Id: 143279
Gene Symbol: HECTD2
HECTD2
Q5U5R9 HECT domain E3 ubiquitin protein ligase 2 8 0.805 0.231 1.00 0.040 None 0.750 4 0 2009 2011
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 Enzyme 689 0.379 0.962 0.18 0.040 None 1.000 4 0 2002 2019
Entrez Id: 79594
Gene Symbol: MUL1
MUL1
Q969V5 mitochondrial E3 ubiquitin protein ligase 1 241 0.473 0.808 1.9E-06 0.040 None 1.000 4 0 2009 2017
Entrez Id: 100505887
Gene Symbol: LINC01672
LINC01672
long intergenic non-protein coding RNA 1672 268 0.462 0.846 0.030 None 1.000 3 0 2011 2013
Entrez Id: 3308
Gene Symbol: HSPA4
HSPA4
P34932 heat shock protein family A (Hsp70) member 4 550 0.394 0.923 1.00 0.030 None 1.000 3 0 2000 2019
Entrez Id: 3483
Gene Symbol: IGFALS
IGFALS
P35858 insulin like growth factor binding protein acid labile subunit Receptor 203 0.511 0.846 5.4E-11 0.030 None 1.000 3 0 2002 2019
Entrez Id: 149420
Gene Symbol: PDIK1L
PDIK1L
Q8N165 PDLIM1 interacting kinase 1 like Kinase 138 0.534 0.769 0.26 0.030 None 1.000 3 0 2008 2019
Entrez Id: 4747
Gene Symbol: NEFL
NEFL
P07196 neurofilament light 247 0.488 0.769 0.030 None 1.000 3 0 2018 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.020 None 1.000 2 0 1997 2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.020 None 1.000 2 0 1997 2006
Entrez Id: 503542
Gene Symbol: SPRN
SPRN
Q5BIV9 shadow of prion protein 7 0.839 0.154 0.29 0.020 None 1.000 2 0 2008 2011
Entrez Id: 23295
Gene Symbol: MGRN1
MGRN1
O60291 mahogunin ring finger 1 Enzyme 8 0.839 0.192 0.10 0.020 None 0.500 2 0 2013 2017
Entrez Id: 2395
Gene Symbol: FXN
FXN
Q16595 frataxin Enzyme 220 0.510 0.654 0.34 0.020 None 1.000 2 0 2007 2018
Entrez Id: 3375
Gene Symbol: IAPP
IAPP
P10997 islet amyloid polypeptide Signaling 183 0.507 0.808 3.2E-03 0.020 None 1.000 2 0 2011 2017
Entrez Id: 2821
Gene Symbol: GPI
GPI
P06744 glucose-6-phosphate isomerase Enzyme 218 0.491 0.769 2.8E-06 0.020 None 1.000 2 0 2001 2018