Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
Q06124 protein tyrosine phosphatase non-receptor type 11 702 0.385 0.923 1.00 1.000 definitive 0.982 112 15 2001 2019
Entrez Id: 10848
Gene Symbol: PPP1R13L
PPP1R13L
Q8WUF5 protein phosphatase 1 regulatory subunit 13 like 122 0.539 0.692 3.2E-02 0.300 strong 1.000 3 0 2005 2015
Entrez Id: 1950
Gene Symbol: EGF
EGF
P01133 epidermal growth factor 774 0.357 0.923 8.5E-17 0.010 None 1.000 1 0 2010 2010
Entrez Id: 23328
Gene Symbol: SASH1
SASH1
O94885 SAM and SH3 domain containing 1 67 0.599 0.538 1.8E-03 0.010 None 1.000 1 0 2016 2016
Entrez Id: 3667
Gene Symbol: IRS1
IRS1
P35568 insulin receptor substrate 1 233 0.488 0.769 2.4E-02 0.010 None 1.000 1 0 2011 2011
Entrez Id: 52
Gene Symbol: ACP1
ACP1
P24666 acid phosphatase 1 107 0.566 0.731 1.8E-08 0.010 None 1.000 1 1 2005 2005
Entrez Id: 54997
Gene Symbol: TESC
TESC
Q96BS2 tescalcin 97 0.570 0.692 0.11 0.010 None 1.000 1 0 2011 2011
Entrez Id: 7248
Gene Symbol: TSC1
TSC1
Q92574 TSC complex subunit 1 391 0.440 0.808 1.00 0.010 None 1.000 1 0 2011 2011
Entrez Id: 79577
Gene Symbol: CDC73
CDC73
Q6P1J9 cell division cycle 73 144 0.543 0.615 1.00 0.010 None 1.000 1 0 2016 2016
Entrez Id: 8036
Gene Symbol: SHOC2
SHOC2
Q9UQ13 SHOC2 leucine rich repeat scaffold protein 97 0.593 0.769 1.00 0.310 1.000 1 0 2011 2011
Entrez Id: 8216
Gene Symbol: LZTR1
LZTR1
Q8N653 leucine zipper like transcription regulator 1 152 0.547 0.808 1.0E-92 0.300 0 0
Entrez Id: 2200
Gene Symbol: FBN1
FBN1
P35555 fibrillin 1 Calcium-binding protein 552 0.417 0.846 1.00 0.010 None 1.000 1 0 2009 2009
Entrez Id: 1832
Gene Symbol: DSP
DSP
P15924 desmoplakin Cellular structure 191 0.514 0.808 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.310 None 1.000 2 2 2001 2005
Entrez Id: 2395
Gene Symbol: FXN
FXN
Q16595 frataxin Enzyme 220 0.510 0.654 0.34 0.010 None 1.000 1 0 2016 2016
Entrez Id: 5500
Gene Symbol: PPP1CB
PPP1CB
P62140 protein phosphatase 1 catalytic subunit beta Enzyme 105 0.601 0.577 1.00 0.300 0 0
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
P01111 NRAS proto-oncogene, GTPase Enzyme modulator 611 0.390 0.808 0.49 0.300 limited 1.000 4 0 2009 2015
Entrez Id: 6654
Gene Symbol: SOS1
SOS1
Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 261 0.485 0.808 1.00 0.330 1.000 3 1 2008 2012
Entrez Id: 4763
Gene Symbol: NF1
NF1
P21359 neurofibromin 1 Enzyme modulator 380 0.440 0.885 0.90 0.020 None 1.000 2 0 1996 2015
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.310 1.000 1 0 2011 2011
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.310 1.000 1 0 2011 2011
Entrez Id: 144568
Gene Symbol: A2ML1
A2ML1
A8K2U0 alpha-2-macroglobulin like 1 Enzyme modulator 94 0.590 0.692 1.6E-34 0.300 0 0
Entrez Id: 22808
Gene Symbol: MRAS
MRAS
O14807 muscle RAS oncogene homolog Enzyme modulator 113 0.590 0.731 0.92 0.300 0 0
Entrez Id: 5921
Gene Symbol: RASA1
RASA1
P20936 RAS p21 protein activator 1 Enzyme modulator 237 0.481 0.885 1.00 0.300 0 0
Entrez Id: 5922
Gene Symbol: RASA2
RASA2
Q15283 RAS p21 protein activator 2 Enzyme modulator 116 0.579 0.769 7.4E-31 0.300 0 0