Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1017
Gene Symbol: CDK2
CDK2
P24941 cyclin dependent kinase 2 Kinase 270 0.456 0.692 0.61 0.010 None 1.000 1 0 1995 1995
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.010 None 1.000 1 0 1995 1995
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.030 None 1.000 3 0 1997 2017
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
P04818 thymidylate synthetase Enzyme 406 0.425 0.846 0.72 0.020 None 1.000 2 0 2002 2015
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.010 None 1.000 1 1 2004 2004
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.100 None 0.960 126 4 2005 2020
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 739 0.362 0.923 1.8E-02 0.020 None 1.000 2 0 2005 2014
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM
P16422 epithelial cell adhesion molecule 328 0.451 0.885 1.3E-07 0.020 None 1.000 2 0 2005 2018
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
P48061 C-X-C motif chemokine ligand 12 626 0.379 0.846 0.12 0.020 None 1.000 2 0 2005 2014
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.010 None 1.000 1 0 2005 2005
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 824 0.353 0.885 2.1E-06 0.010 None 1.000 1 0 2009 2009
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.080 None 1.000 8 1 2010 2018
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 345 0.445 0.846 1.6E-07 0.030 None 1.000 3 0 2010 2012
Entrez Id: 1136
Gene Symbol: CHRNA3
CHRNA3
P32297 cholinergic receptor nicotinic alpha 3 subunit Ion channel 110 0.588 0.692 1.4E-07 0.010 None 1.000 1 1 2010 2010
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.010 None 1.000 1 0 2010 2010
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.030 None 1.000 3 0 2011 2012
Entrez Id: 55743
Gene Symbol: CHFR
CHFR
Q96EP1 checkpoint with forkhead and ring finger domains Enzyme 56 0.633 0.500 7.9E-04 0.020 None 1.000 2 0 2011 2013
Entrez Id: 84654
Gene Symbol: SPZ1
SPZ1
Q9BXG8 spermatogenic leucine zipper 1 173 0.507 0.769 0.010 None 1.000 1 0 2011 2011
Entrez Id: 92140
Gene Symbol: MTDH
MTDH
Q86UE4 metadherin 200 0.491 0.769 0.33 0.010 None 1.000 1 0 2011 2011
Entrez Id: 7057
Gene Symbol: THBS1
THBS1
P07996 thrombospondin 1 480 0.407 0.885 1.00 0.010 None 1.000 1 0 2011 2011
Entrez Id: 7180
Gene Symbol: CRISP2
CRISP2
P16562 cysteine rich secretory protein 2 Immune response 168 0.512 0.769 1.4E-12 0.010 None 1.000 1 0 2011 2011
Entrez Id: 203074
Gene Symbol: PRSS55
PRSS55
Q6UWB4 serine protease 55 Enzyme 163 0.513 0.769 3.2E-11 0.010 None 1.000 1 0 2011 2011
Entrez Id: 54458
Gene Symbol: PRR13
PRR13
Q9NZ81 proline rich 13 11 0.769 0.308 1.4E-02 0.010 None 1.000 1 0 2011 2011
Entrez Id: 238
Gene Symbol: ALK
ALK
Q9UM73 ALK receptor tyrosine kinase Kinase 519 0.396 0.846 3.2E-06 0.100 None 0.957 47 0 2012 2019
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1
Q15672 twist family bHLH transcription factor 1 Transcription factor 559 0.397 0.846 0.34 0.030 None 1.000 3 0 2012 2019