Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.400 None 0.977 44 4 1994 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.100 None 1.000 34 0 1999 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.400 None 0.958 24 0 2000 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.400 None 1.000 14 5 1997 2018
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
MT-CO2 pseudogene 12 703 0.368 0.962 0.100 None 1.000 13 0 2000 2019
Entrez Id: 4513
Gene Symbol: COX2
COX2
P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.100 None 1.000 13 0 2000 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.100 None 1.000 11 0 2006 2018
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.100 None 1.000 10 0 2005 2019
Entrez Id: 79400
Gene Symbol: NOX5
NOX5
Q96PH1 NADPH oxidase 5 57 0.631 0.538 3.0E-28 0.100 None 1.000 10 0 2006 2016
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.090 None 1.000 9 0 1999 2015
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
H3 histone pseudogene 10 769 0.350 0.846 0.090 None 1.000 9 0 1997 2018
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.070 None 0.857 7 0 2000 2013
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM
P16422 epithelial cell adhesion molecule 328 0.451 0.885 1.3E-07 0.070 None 1.000 7 0 2001 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.070 None 0.857 7 0 2016 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.350 None 1.000 6 0 2006 2017
Entrez Id: 1045
Gene Symbol: CDX2
CDX2
Q99626 caudal type homeobox 2 Transcription factor 278 0.458 0.769 0.53 0.060 None 1.000 6 0 2004 2013
Entrez Id: 1950
Gene Symbol: EGF
EGF
P01133 epidermal growth factor 774 0.357 0.923 8.5E-17 0.060 None 1.000 6 0 2008 2016
Entrez Id: 1666
Gene Symbol: DECR1
DECR1
Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 399 0.426 0.885 4.5E-14 0.050 None 1.000 5 0 2007 2011
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
P23219 prostaglandin-endoperoxide synthase 1 Enzyme 318 0.460 0.885 6.2E-07 0.240 None 1.000 5 0 2001 2012
Entrez Id: 558
Gene Symbol: AXL
AXL
P30530 AXL receptor tyrosine kinase Kinase 203 0.489 0.615 1.3E-02 0.050 None 1.000 5 0 2010 2018
Entrez Id: 4512
Gene Symbol: COX1
COX1
P00395 cytochrome c oxidase subunit I Enzyme 421 0.441 0.885 0.050 None 1.000 5 0 2001 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.050 None 1.000 5 0 2017 2020
Entrez Id: 2247
Gene Symbol: FGF2
FGF2
P09038 fibroblast growth factor 2 Signaling 635 0.383 0.923 1.8E-02 0.050 None 1.000 5 0 1999 2010
Entrez Id: 56033
Gene Symbol: BARX1
BARX1
Q9HBU1 BARX homeobox 1 Transcription factor 17 0.751 0.308 0.59 0.430 None 1.000 4 1 2013 2018
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 499 0.420 0.846 7.1E-20 0.040 None 1.000 4 4 2005 2014