Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4353
Gene Symbol: MPO
MPO
P05164 myeloperoxidase Enzyme 653 0.377 0.923 7.1E-15 0.030 None 0.667 3 0 1987 1995
Entrez Id: 100
Gene Symbol: ADA
ADA
P00813 adenosine deaminase Enzyme 379 0.440 0.885 2.9E-12 0.010 None 1.000 1 0 1984 1984
Entrez Id: 10642
Gene Symbol: IGF2BP1
IGF2BP1
Q9NZI8 insulin like growth factor 2 mRNA binding protein 1 Enzyme 106 0.560 0.692 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 1511
Gene Symbol: CTSG
CTSG
P08311 cathepsin G Enzyme 95 0.563 0.731 9.6E-06 0.010 None 1.000 1 0 2009 2009
Entrez Id: 246
Gene Symbol: ALOX15
ALOX15
P16050 arachidonate 15-lipoxygenase Enzyme 205 0.502 0.846 1.1E-23 0.010 None 1.000 1 0 2014 2014
Entrez Id: 290
Gene Symbol: ANPEP
ANPEP
P15144 alanyl aminopeptidase, membrane Enzyme 280 0.462 0.769 3.7E-09 0.010 None 1.000 1 0 1992 1992
Entrez Id: 4311
Gene Symbol: MME
MME
P08473 membrane metalloendopeptidase Enzyme 470 0.407 0.808 1.5E-18 0.010 None 1.000 1 0 1985 1985
Entrez Id: 57060
Gene Symbol: PCBP4
PCBP4
P57723 poly(rC) binding protein 4 Enzyme 147 0.523 0.808 2.4E-03 0.010 None 1.000 1 0 2010 2010
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase Enzyme 703 0.374 0.846 0.99 0.010 None 1.000 1 0 2016 2016
Entrez Id: 842
Gene Symbol: CASP9
CASP9
P55211 caspase 9 Enzyme 293 0.458 0.808 7.4E-06 0.010 None 1.000 1 0 2015 2015
Entrez Id: 6418
Gene Symbol: SET
SET
Q01105 SET nuclear proto-oncogene Enzyme modulator 183 0.507 0.808 1.00 0.100 None 0.909 11 0 1992 2010
Entrez Id: 613
Gene Symbol: BCR
BCR
P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 392 0.431 0.885 0.99 0.040 None 1.000 4 0 1995 2019
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
P01111 NRAS proto-oncogene, GTPase Enzyme modulator 611 0.390 0.808 0.49 0.010 None 1.000 1 1 2014 2014
Entrez Id: 6237
Gene Symbol: RRAS
RRAS
P10301 RAS related Enzyme modulator 149 0.543 0.808 4.7E-03 0.010 None 1.000 1 0 2015 2015
Entrez Id: 23028
Gene Symbol: KDM1A
KDM1A
O60341 lysine demethylase 1A Epigenetic regulator 185 0.512 0.808 1.00 0.020 None 1.000 2 0 2012 2016
Entrez Id: 10765
Gene Symbol: KDM5B
KDM5B
Q9UGL1 lysine demethylase 5B Epigenetic regulator 162 0.532 0.731 7.9E-15 0.010 None 1.000 1 0 2015 2015
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 653 0.376 0.885 1.00 0.010 None 1.000 1 0 2014 2014
Entrez Id: 8932
Gene Symbol: MBD2
MBD2
Q9UBB5 methyl-CpG binding domain protein 2 Epigenetic regulator 256 0.466 0.846 0.35 0.010 None 1.000 1 0 2012 2012
Entrez Id: 30817
Gene Symbol: ADGRE2
ADGRE2
Q9UHX3 adhesion G protein-coupled receptor E2 G-protein coupled receptor 86 0.581 0.615 2.8E-28 0.020 None 1.000 2 0 2019 2019
Entrez Id: 976
Gene Symbol: ADGRE5
ADGRE5
P48960 adhesion G protein-coupled receptor E5 G-protein coupled receptor 74 0.601 0.538 3.1E-06 0.020 None 1.000 2 0 2019 2019
Entrez Id: 2149
Gene Symbol: F2R
F2R
P25116 coagulation factor II thrombin receptor G-protein coupled receptor 347 0.444 0.846 8.5E-03 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5956
Gene Symbol: OPN1LW
OPN1LW
P04000 opsin 1, long wave sensitive G-protein coupled receptor 197 0.497 0.808 0.98 0.010 None 1.000 1 0 2010 2010
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 739 0.362 0.923 1.8E-02 0.010 None 1.000 1 0 2019 2019
Entrez Id: 25
Gene Symbol: ABL1
ABL1
P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 395 0.432 0.923 1.00 0.020 None 1.000 2 0 2007 2019
Entrez Id: 1436
Gene Symbol: CSF1R
CSF1R
P07333 colony stimulating factor 1 receptor Kinase 356 0.448 0.808 0.13 0.010 None 1.000 1 0 2010 2010